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确定周围神经修复患者手部的功能感觉:使用新型手动触觉测试监测神经再生进展的可行性。

Determining the functional sensibility of the hand in patients with peripheral nerve repair: Feasibility of using a novel manual tactile test for monitoring the progression of nerve regeneration.

作者信息

Hsu Hsiu-Yun, Kuo Li-Chieh, Kuan Ta-Shen, Yang Hsiu-Ching, Su Fong-Chin, Chiu Haw-Yen, Shieh Shyh-Jou

机构信息

Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Occupational Therapy, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Medical Device Innovation Center, National Cheng Kung University, Tainan, Taiwan.

Department of Occupational Therapy, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Medical Device Innovation Center, National Cheng Kung University, Tainan, Taiwan.

出版信息

J Hand Ther. 2017 Jan-Mar;30(1):65-73. doi: 10.1016/j.jht.2016.03.004.

DOI:10.1016/j.jht.2016.03.004
PMID:28317655
Abstract

STUDY DESIGN

Case-controlled cohort study.

INTRODUCTION

Sensory function is difficult to observe during nerve regeneration processes. Traditional sensory tests are limited to identifying the level of functioning hand sensation for sensory stimulus is given passively to the cutaneous surface of the hand.

PURPOSE OF THE STUDY

To examine the outcome changes in the manual tactile test (MTT), Semmes-Weinstein monofilament (SWM) and 2-point discrimination (2PD) tests for patients with nerve repair and to investigate the concurrent validity of MTT by comparing it with the results of traditional tests.

METHODS

Fifteen patients with nerve injury of the upper limbs were recruited, along with 15 matched healthy controls. The MTT, SWM, and 2PD tests were used to examine the sensory status of the subjects.

RESULTS

Three subtests (barognosis, roughness differentiation, and stereognosis) in MTT showed that the patients improved with time. A moderate and mild correlation was found between the MTT and 2PD results and between the barognosis and SWM results.

CONCLUSIONS

The MTT provides practical and functional perspectives on detecting nerve progression during the courses of degeneration and regeneration.

LEVEL OF EVIDENCE

IV.

摘要

研究设计

病例对照队列研究。

引言

在神经再生过程中,感觉功能难以观察。传统的感觉测试仅限于识别手部感觉功能水平,因为感觉刺激是被动施加于手部皮肤表面的。

研究目的

检查神经修复患者在手动触觉测试(MTT)、Semmes-Weinstein单丝(SWM)和两点辨别(2PD)测试中的结果变化,并通过将MTT与传统测试结果进行比较来研究MTT的同时效度。

方法

招募了15例上肢神经损伤患者以及15例匹配的健康对照。使用MTT、SWM和2PD测试来检查受试者的感觉状态。

结果

MTT中的三个子测试(重量觉、粗糙度辨别和实体觉)表明患者随时间有所改善。MTT与2PD结果之间以及重量觉与SWM结果之间存在中度和轻度相关性。

结论

MTT为检测退变和再生过程中的神经进展提供了实用和功能方面的视角。

证据水平

四级。

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