疑似眼内结核的视觉发病率和眼部并发症：来自非流行区的 354 例分析。
Visual Morbidity and Ocular Complications in Presumed Intraocular Tuberculosis: An Analysis of 354 Cases from a Non-Endemic Population.
机构信息
a National Healthcare Group Eye Institute, Tan Tock Seng Hospital , Singapore , Singapore.
b Moorfields Eye Hospital, NHS Foundation Trust , London , UK.
出版信息
Ocul Immunol Inflamm. 2018;26(6):865-869. doi: 10.1080/09273948.2017.1296580. Epub 2017 Mar 20.
PURPOSE
To describe the visual morbidity associated with intraocular tuberculosis (TB) and to report ocular complications of intraocular TB.
METHODS
Retrospective cohort study of patients diagnosed with intraocular TB at a tertiary referral eye care hospital in central London. Data on baseline and final best-corrected visual acuity (BCVA) along with ocular complications were collected and analyzed.
RESULTS
In total, 354 patients with intraocular TB were included in this study. Mean age was 48.45 years (range 19-94) and follow-up was 22.56 ± 7.44 (range 6-30) months post cessation of therapy. Blindness as defined by the World Health Organization was reported in 11 (3.11%) patients at baseline and 13 (3.67%) patients at follow-up. The most common ocular complications were cystoid macular edema (n = 107, 30.5%) and glaucoma (n = 99, 28.12%).
CONCLUSION
Intraocular TB can be associated with significant ocular morbidity. Early recognition, treatment, and regular follow-up of this complex disease may help to reduce visual morbidity and ocular complications.
目的
描述眼内结核（TB）相关的视觉发病率，并报告眼内 TB 的眼部并发症。
方法
对伦敦市中心一家三级转诊眼科医院诊断为眼内 TB 的患者进行回顾性队列研究。收集并分析了基线和最终最佳矫正视力（BCVA）以及眼部并发症的数据。
结果
本研究共纳入 354 例眼内 TB 患者。平均年龄为 48.45 岁（19-94 岁），治疗停止后随访 22.56±7.44 个月（6-30 个月）。基线时有 11 名（3.11%）患者和随访时有 13 名（3.67%）患者报告失明符合世界卫生组织的定义。最常见的眼部并发症是黄斑囊样水肿（n=107，30.5%）和青光眼（n=99，28.12%）。
结论
眼内 TB 可导致严重的眼部发病率。早期识别、治疗和定期随访这种复杂疾病可能有助于降低视觉发病率和眼部并发症。
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