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结直肠息肉管理与切除技术的当前标准及新进展

Current standards and new developments of colorectal polyp management and resection techniques.

作者信息

Von Renteln Daniel, Bouin Mickael, Barkun Alan N

机构信息

a Department of Medicine, Division of Gastroenterology , Montreal University Hospital (CHUM) , Montreal , Canada.

b Division of Gastroenterology , McGill University Health Center, McGill University , Montreal , Quebec , Canada.

出版信息

Expert Rev Gastroenterol Hepatol. 2017 Sep;11(9):835-842. doi: 10.1080/17474124.2017.1309279. Epub 2017 May 23.

Abstract

Colonoscopy and endoscopic removal of precancerous polyps play an important role in colorectal cancer (CRC) prevention. Improved endoscopes and quality standards have led to an increasing polyp and adenoma detection rate. Optimal polyp resection techniques and management strategies are key for an effective colonoscopy practice. Areas covered: Strategies for how to improve diminutive polyp (polyps up to 5 mm in size) management are discussed because of their high prevalence. Systematic removal of diminutive polyps leads to increasing costs of colonoscopy practice, while the effect on colorectal cancer prevention might be negligible. Furthermore, polypectomy recommendations for mid-size and large polyps are provided. For all larger polyps larger, complete and safe resection is mandatory to avoid post colonoscopy cancers. The focus for managing such larger polyps is to use new techniques (i.e. cold snares) and to attempt complete removal and to reduce post-polypectomy complications. Expert commentary: The resect-and-discard strategy is a promising management strategy for diminutive polyps. However, modification of this approach might be required in order to make widespread adoption feasible. Cold snare polypectomy is a promising new approach for small polyp resection. For resection of large polyps adequate treatment recommendations with regard to endoscopic mucosal resection and complication prevention are provided.

摘要

结肠镜检查及内镜下切除癌前息肉在结直肠癌(CRC)预防中发挥着重要作用。内镜及质量标准的改进使得息肉及腺瘤的检出率不断提高。最佳的息肉切除技术及管理策略是有效开展结肠镜检查的关键。涵盖领域:由于微小息肉(直径达5毫米的息肉)患病率高,因此讨论了改善其管理的策略。系统性切除微小息肉会导致结肠镜检查成本增加,而对结直肠癌预防的效果可能微不足道。此外,还提供了对中等大小和大息肉的息肉切除建议。对于所有较大的息肉,必须进行完整且安全的切除以避免结肠镜检查后发生癌症。处理此类较大息肉的重点是采用新技术(如冷圈套器),尝试完整切除并减少息肉切除术后并发症。专家评论:切除并丢弃策略是一种很有前景的微小息肉管理策略。然而,可能需要对该方法进行调整,以便能够广泛采用。冷圈套器息肉切除术是一种很有前景的小息肉切除新方法。对于大息肉的切除,提供了关于内镜黏膜切除术及并发症预防的适当治疗建议。

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