11C-蛋氨酸PET及DSC灌注MRI上酷似肿瘤的发育性静脉异常
Developmental Venous Anomalies Mimicking Neoplasm on 11C-Methionine PET and DSC Perfusion MRI.
作者信息
Harreld Julie H, Doubrovin Mikhail, Butch Elizabeth R, Edwards Angela, Shulkin Barry
机构信息
From the Department of Diagnostic Imaging, St Jude Children's Research Hospital, Memphis, TN.
出版信息
Clin Nucl Med. 2017 May;42(5):e275-e276. doi: 10.1097/RLU.0000000000001637.
Abstract
Elevated relative cerebral blood volume on perfusion MRI and increased uptake on C-methionine PET can be used to diagnose and guide biopsy of brain tumors but are not specific. We report increased uptake on C-methionine PET associated with 4 developmental venous anomalies (DVAs) in 3 children with brain tumors, which could potentially mimic tumor and misdirect biopsy. Because DVAs are not readily visible on CT, prevention of misdirected biopsy in patients with focally elevated C-methionine uptake and relative cerebral blood volume relies on close correlation with contrast-enhanced anatomic MRI to exclude DVA or other nonneoplastic etiology.
摘要
灌注磁共振成像（MRI）上相对脑血容量升高以及¹¹C-蛋氨酸正电子发射断层扫描（PET）上摄取增加可用于诊断和指导脑肿瘤活检，但缺乏特异性。我们报告了3例脑肿瘤患儿中，¹¹C-蛋氨酸PET上的摄取增加与4个发育性静脉异常（DVA）相关，这可能会模拟肿瘤并导致活检方向错误。由于DVA在CT上不易显示，对于¹¹C-蛋氨酸摄取和相对脑血容量局部升高的患者，防止活检方向错误依赖于与增强解剖MRI密切对照，以排除DVA或其他非肿瘤性病因。
相似文献
1
Developmental Venous Anomalies Mimicking Neoplasm on 11C-Methionine PET and DSC Perfusion MRI.11C-蛋氨酸PET及DSC灌注MRI上酷似肿瘤的发育性静脉异常
Clin Nucl Med. 2017 May;42(5):e275-e276. doi: 10.1097/RLU.0000000000001637.
2
Whole-tumor histogram analysis of the cerebral blood volume map: tumor volume defined by 11C-methionine positron emission tomography image improves the diagnostic accuracy of cerebral glioma grading.脑血容量图的全肿瘤直方图分析：由11C-蛋氨酸正电子发射断层扫描图像定义的肿瘤体积可提高脑胶质瘤分级的诊断准确性。
Jpn J Radiol. 2017 Oct;35(10):613-621. doi: 10.1007/s11604-017-0675-2. Epub 2017 Sep 6.
3
Evaluation of sporadic intracranial cavernous malformations for detecting associated developmental venous anomalies: added diagnostic value of C-arm contrast-enhanced cone-beam CT to routine contrast-enhanced MRI.评价颅内海绵状血管畸形以检测相关的发育性静脉异常：C 臂增强锥形束 CT 对常规增强 MRI 的附加诊断价值。
Eur Radiol. 2019 Feb;29(2):783-791. doi: 10.1007/s00330-018-5652-3. Epub 2018 Jul 31.
4
Spatial distribution of malignant tissue in gliomas: correlations of 11C-L-methionine positron emission tomography and perfusion- and diffusion-weighted magnetic resonance imaging.神经胶质瘤中恶性组织的空间分布：11C-L-蛋氨酸正电子发射断层扫描与灌注加权和扩散加权磁共振成像的相关性
Acta Radiol. 2015 Sep;56(9):1135-44. doi: 10.1177/0284185114550020. Epub 2014 Sep 30.
5
Differentiating radiation necrosis from tumor recurrence in high-grade gliomas: assessing the efficacy of 18F-FDG PET, 11C-methionine PET and perfusion MRI.高级别胶质瘤中放射性坏死与肿瘤复发的鉴别：评估18F-FDG PET、11C-蛋氨酸PET及灌注MRI的效能
Clin Neurol Neurosurg. 2010 Nov;112(9):758-65. doi: 10.1016/j.clineuro.2010.06.005. Epub 2010 Jul 8.
6
Association of developmental venous anomalies with perfusion abnormalities on arterial spin labeling and bolus perfusion-weighted imaging.发育性静脉异常与动脉自旋标记和团注灌注加权成像上灌注异常的相关性
J Neuroimaging. 2015 Mar-Apr;25(2):243-250. doi: 10.1111/jon.12119. Epub 2014 Apr 9.
7
Glioma grading by dynamic susceptibility contrast perfusion and C-methionine positron emission tomography using different regions of interest.应用不同感兴趣区的动态磁敏感对比灌注和 C-蛋氨酸正电子发射断层成像对胶质瘤进行分级。
Neuroradiology. 2018 Apr;60(4):381-389. doi: 10.1007/s00234-018-1993-5. Epub 2018 Feb 20.
8
Transient Focal Magnetic Resonance Imaging Abnormalities After Status Epilepticus Showed 11C-Methionine Uptake with Positron Emission Tomography in a Patient with Cerebral Cavernous Malformation.癫痫持续状态后短暂局灶性磁共振成像异常的患者，经正电子发射断层扫描显示 11C-蛋氨酸摄取增加，该患者患有脑海绵状血管畸形。
World Neurosurg. 2018 Jun;114:43-46. doi: 10.1016/j.wneu.2018.03.020. Epub 2018 Mar 10.
9
A pitfall of C-11 methionine PET: cerebral venous infarction mimicked a glioma.碳-11蛋氨酸正电子发射断层扫描（PET）的一个陷阱：脑静脉梗死被误诊为胶质瘤。
Clin Nucl Med. 2012 Jan;37(1):110-1. doi: 10.1097/RLU.0b013e3182336433.
10
Perfusion-CT of developmental venous anomalies: typical and atypical hemodynamic patterns.发育性静脉畸形的灌注 CT：典型和非典型血流动力学模式。
J Neuroradiol. 2010 Oct;37(4):239-42. doi: 10.1016/j.neurad.2009.09.002. Epub 2009 Dec 2.
引用本文的文献
1
Joint EANM/SIOPE/RAPNO practice guidelines/SNMMI procedure standards for imaging of paediatric gliomas using PET with radiolabelled amino acids and [F]FDG: version 1.0.使用放射性标记氨基酸和 [F]FDG 的 PET 成像儿童脑胶质瘤的 EANM/SIOPE/RAPNO 实践指南/SNMMI 程序标准：第 1.0 版。
Eur J Nucl Med Mol Imaging. 2022 Sep;49(11):3852-3869. doi: 10.1007/s00259-022-05817-6. Epub 2022 May 10.
本文引用的文献
1
Increased Prevalence of Developmental Venous Anomalies in Children with Intracranial Neoplasms.颅内肿瘤患儿中发育性静脉异常的患病率增加。
AJNR Am J Neuroradiol. 2015 Sep;36(9):1782-5. doi: 10.3174/ajnr.A4352. Epub 2015 May 28.
2
Brain metabolic abnormalities associated with developmental venous anomalies.与发育性静脉异常相关的脑代谢异常。
AJNR Am J Neuroradiol. 2015 Mar;36(3):475-80. doi: 10.3174/ajnr.A4172. Epub 2014 Dec 4.
3
Brain parenchymal signal abnormalities associated with developmental venous anomalies in children and young adults.儿童和青年中与发育性静脉异常相关的脑实质信号异常。
AJNR Am J Neuroradiol. 2014 Aug;35(8):1600-7. doi: 10.3174/ajnr.A3960. Epub 2014 May 15.
4
Hemodynamic effects of developmental venous anomalies with and without cavernous malformations.伴有和不伴有海绵状血管畸形的发育性静脉异常的血液动力学效应。
AJNR Am J Neuroradiol. 2013 Sep;34(9):1746-51. doi: 10.3174/ajnr.A3516. Epub 2013 Apr 18.
5
[18F]-fluoro-ethyl-L-tyrosine PET: a valuable diagnostic tool in neuro-oncology, but not all that glitters is glioma.18F-氟乙基-L-酪氨酸 PET：神经肿瘤学中一种有价值的诊断工具，但并非所有闪闪发光的都是神经胶质瘤。
Neuro Oncol. 2013 Mar;15(3):341-51. doi: 10.1093/neuonc/nos300. Epub 2013 Jan 17.
6
[11C-methionine positron emission tomography in nontumorous brain lesions].[¹¹C-蛋氨酸正电子发射断层扫描在非肿瘤性脑病变中的应用]
No Shinkei Geka. 2010 Nov;38(11):985-95.
7
Stereotactic comparison among cerebral blood volume, methionine uptake, and histopathology in brain glioma.脑胶质瘤中脑血容量、蛋氨酸摄取与组织病理学的立体定向比较。
AJNR Am J Neuroradiol. 2007 Mar;28(3):455-61.
8
High-grade and low-grade gliomas: differentiation by using perfusion MR imaging.高级别和低级别胶质瘤：利用灌注磁共振成像进行鉴别
Clin Radiol. 2005 Apr;60(4):493-502. doi: 10.1016/j.crad.2004.09.009.
9
Cerebral hemodynamics in human acute ischemic stroke: a study with diffusion- and perfusion-weighted magnetic resonance imaging and SPECT.人类急性缺血性卒中的脑血流动力学：一项采用扩散加权磁共振成像、灌注加权磁共振成像和单光子发射计算机断层扫描的研究
J Cereb Blood Flow Metab. 2000 Jun;20(6):910-20. doi: 10.1097/00004647-200006000-00003.
10
Amino acid uptake in ischemically compromised brain tissue.缺血性受损脑组织中的氨基酸摄取。
Stroke. 1995 Oct;26(10):1859-66. doi: 10.1161/01.str.26.10.1859.
Zotero 插件