Govindappagari S, Zork N, Merriam A, Gyamfi-Bannerman C
Department of Obstetrics and Gynecology, New York Presbyterian Hospital/Queens, Weill Cornell College of Medicine, New York, New York.
Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, New York.
Am J Perinatol. 2017 Jul;34(9):922-926. doi: 10.1055/s-0037-1601310. Epub 2017 Mar 20.
Our objective was to determine if the relationship between interpregnancy interval (IPI) and preterm delivery was related to cervical shortening. This is a secondary analysis of a prospective cohort study designed to assess the relationship between cervical length (CL) and preterm delivery. Multiparous patients, who had transvaginal CLs obtained at 22 to 24 weeks and complete pregnancy outcome data available were included. The women were divided into two groups: Group 1 with an IPI of ≤ 1 year and Group 2 with an IPI of > 1 year. The primary outcome was short cervix (CL < 2.5 cm) at 24 weeks. The secondary outcome was the incidence of preterm delivery < 37 weeks. Interaction between short cervix and IPI was examined in a regression model. There were 155 women in Group 1 and 328 women in Group 2. There was no difference in the incidence of short cervix between groups (10.0% in Group 1 and 12.9% in Group 2, = 0.35). In a logistic regression model, short IPI and short cervix were independently associated with preterm birth. The relationship between short IPI and preterm birth is not explained by a short cervix. They remain independent risk factors for preterm birth.
我们的目标是确定妊娠间隔期（IPI）与早产之间的关系是否与宫颈缩短有关。 这是一项前瞻性队列研究的二次分析，旨在评估宫颈长度（CL）与早产之间的关系。纳入了在22至24周时进行经阴道CL测量且有完整妊娠结局数据的经产妇。这些女性被分为两组：第1组IPI≤1年，第2组IPI>1年。主要结局是24周时宫颈短（CL<2.5 cm）。次要结局是孕周<37周的早产发生率。在回归模型中检验宫颈短与IPI之间的相互作用。 第1组有155名女性，第2组有328名女性。两组之间宫颈短的发生率没有差异（第1组为10.0%，第2组为12.9%，P=0.35）。在逻辑回归模型中，短IPI和宫颈短与早产独立相关。 短IPI与早产之间的关系不能用宫颈短来解释。它们仍然是早产的独立危险因素。
