Lentle B C, Catz Z, Dierich H C, Scott J R, Hooper H R
Division of Nuclear Medicine, Vancouver General Hospital, BC.
CMAJ. 1987 Nov 1;137(9):815-7.
Gallium-67 scintigraphy has been of limited use in detecting lung cancers and micrometastases. To study its potential for determining the aggressiveness of a cancer, we reviewed the charts of 44 patients with non-small-cell bronchogenic carcinoma who had not been receiving treatment when 67Ga scintigraphy was performed. The mean length of survival for the 18 patients with low or little uptake of the tracer, corrected for tumour size, was 19.7 months, and for the 26 with high uptake 9.4 months (p less than 0.01). Such in-vivo predictive assays may be a rational goal for tumour scintigraphy.
镓-67闪烁扫描术在检测肺癌及微转移方面的应用有限。为研究其在确定癌症侵袭性方面的潜力，我们回顾了44例非小细胞支气管癌患者的病历，这些患者在进行镓-67闪烁扫描术时未接受治疗。经肿瘤大小校正后，示踪剂摄取量低或极少的18例患者的平均生存期为19.7个月，而摄取量高的26例患者为9.4个月（P<0.01）。这种体内预测性检测可能是肿瘤闪烁扫描术的一个合理目标。
