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永久性球部尿道结扎术:终末期尿道尿失禁男性的新兴治疗选择

Permanent Bulbar Urethral Ligation: Emerging Treatment Option for Incontinent Men With End-stage Urethra.

作者信息

VanDyke Maia E, Viers Boyd R, Pagliara Travis J, Scott Jeremy M, Shakir Nabeel, Dugi Daniel D, Cordon Billy H, Hofer Matthias D, Morey Allen F

机构信息

Department of Urology, University of Texas Southwestern, Dallas, TX.

Department of Urology, Oregon Health & Science University, Portland, OR.

出版信息

Urology. 2017 Jul;105:186-191. doi: 10.1016/j.urology.2017.02.042. Epub 2017 Mar 18.

Abstract

OBJECTIVE

To report our experience with permanent urethral ligation for severe incontinence among men with end-stage urethra.

MATERIALS AND METHODS

From our institutional artificial urinary sphincter database of 512 patients from 2010 to 2016, 10 men underwent permanent urethral ligation with concurrent suprapubic tube diversion following recurrent artificial urinary sphincter cuff erosion. Clinical characteristics and outcomes were evaluated. Quality of life was assessed using the Michigan Incontinence Symptom Index and the Patient Global Index of Improvement.

RESULTS

Urethral ligation resulted in resolution of incontinence in 8 men (80%), including 7 (70%) after 1 surgery and in 1 (10%) after a single revision. The average American Society of Anesthesiologists physical status rating was 2.7 (range 2-3). Seven patients (70%) experienced postoperative complications (4 Clavien-Dindo grade II complications [1 Clostridium difficile infection, 3 refractory bladder spasms) and 5 grade III complications (2 abscesses, 2 urethrocutaneous fistula, and 1 bladder stone formation]). Overall, satisfactory Michigan Incontinence Symptom Index urinary scores were reported in 8 (80%) men. On the Patient Global Index of Improvement, 6 (60%) men reported improvement in overall condition following surgery. All men (10/10) stated that they would recommend this procedure to others.

CONCLUSION

For debilitated men with end-stage urethra and severe refractory stress urinary incontinence, permanent urethral ligation with chronic suprapubic tube drainage can restore continence and improve quality of life without the need for more invasive formal urinary diversion, though with a high risk of complication.

摘要

目的

报告我们对终末期尿道男性患者进行永久性尿道结扎治疗严重尿失禁的经验。

材料与方法

从我们机构2010年至2016年的512例人工尿道括约肌数据库中,10例男性在人工尿道括约肌袖带反复侵蚀后接受了永久性尿道结扎并同时进行耻骨上造瘘管引流。评估临床特征和结果。使用密歇根尿失禁症状指数和患者总体改善指数评估生活质量。

结果

尿道结扎使8例男性(80%)的尿失禁得到解决,其中7例(70%)在1次手术后,1例(10%)在1次翻修后。美国麻醉医师协会身体状况评分平均为2.7(范围2 - 3)。7例患者(70%)出现术后并发症(4例Clavien-Dindo二级并发症[1例艰难梭菌感染,3例难治性膀胱痉挛]和5例三级并发症[2例脓肿,2例尿道皮肤瘘,1例膀胱结石形成])。总体而言,8例(80%)男性报告密歇根尿失禁症状指数尿液评分满意。在患者总体改善指数方面,6例(60%)男性报告术后整体状况有所改善。所有男性(10/10)均表示会向他人推荐该手术。

结论

对于患有终末期尿道且严重难治性压力性尿失禁的体弱男性,永久性尿道结扎并长期耻骨上造瘘管引流可恢复控尿并改善生活质量,无需进行更具侵入性的正规尿路改道,尽管并发症风险较高。

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