Brännström M, Vojinovic O, Nordenvall K J
J Prosthet Dent. 1979 Mar;41(3):290-5. doi: 10.1016/0022-3913(79)90009-x.
Silicate cement was inserted in deep unlined cavities in 70 human teeth; 35 cavities were cleaned with an antibacterial cleanser, and the other 35 cavities in the contralateral teeth were treated with water spray only. In all teeth, invasion of bacteria from the tooth surface was prevented with a surface seal. Histologic examinations after 4 weeks revealed bacterial growth on dentinal walls in 9 of the uncleaned and in 2 cleaned cavities. Only in these 11 teeth was an inflammatory reaction seen in the pulp. Under eight cavities without bacterial growth and with silicate cement placed directly on an exposed pulp, no serious injury and no inflammatory reactions were observed. It was concluded that silicate cement per se does not seriously irritate the pulp. Infection of cavity walls should be avoided, not only by removing grinding debris and antibacterial cleansing, but also by use of a liner to prevent invasion of bacteria from the surface of the tooth.
将硅酸盐水门汀填入70颗人牙的深层无衬洞；35个洞用抗菌清洁剂清洁，对侧牙齿的另外35个洞仅用水冲洗。在所有牙齿中，用表面封闭剂防止细菌从牙齿表面侵入。4周后的组织学检查显示，9个未清洁的洞和2个清洁的洞的牙本质壁上有细菌生长。仅在这11颗牙齿的牙髓中观察到炎症反应。在8个没有细菌生长且硅酸盐水门汀直接置于暴露牙髓上的洞下方，未观察到严重损伤和炎症反应。得出的结论是，硅酸盐水门汀本身不会严重刺激牙髓。应避免洞壁感染，不仅要清除磨削碎屑并进行抗菌清洁，还要使用衬层以防止细菌从牙齿表面侵入。
