Askonas B A, Taylor P M
National Institute for Medical Research, The Ridgeway, Mill Hill, London, U.K.
Immunol Lett. 1987 Dec;16(3-4):337-40. doi: 10.1016/0165-2478(87)90167-2.
Subpopulations of T cells have many different functions which are important for the regulation of immune responses, and as effector cells to rid the host of intracellular virus infections. In this report, we describe a few features of T cells: their viral recognition patterns, the genetics of antiviral T cell responses, and the variation in the function of T cell subpopulations in different virus infections. Our particular emphasis relates to influenza, which is one of the best analysed model systems to date.
T细胞亚群具有许多不同的功能,这些功能对于免疫反应的调节以及作为清除宿主细胞内病毒感染的效应细胞都很重要。在本报告中,我们描述了T细胞的一些特征:它们的病毒识别模式、抗病毒T细胞反应的遗传学以及不同病毒感染中T细胞亚群功能的差异。我们特别强调的是流感,它是迄今为止分析得最好的模型系统之一。