Yang Ting-Hua, Chen Hsin-Lin, Young Yi-Ho
a Department of Otolaryngology , National Taiwan University Hospital , Taipei , Taiwan.
Acta Otolaryngol. 2017 Aug;137(8):807-813. doi: 10.1080/00016489.2017.1286037. Epub 2017 Mar 21.
This study investigated the influence of pathological eye movements on the recordings of ocular vestibulo-evoked myogenic potential (oVEMP).
Ten patients with pathological eye movements of non-vestibular origin (nine congenital nystagmus and one opsoclonus) who had negative MRI result were assigned to Group A. Another 20 vestibular neuritis (VN) patients with spontaneous nystagmus were assigned to Group B. Both groups underwent audiometry, and caloric, oVEMP and cervical VEMP (cVEMP) tests.
In Group A, the caloric, oVEMP and cVEMP tests showed 40%, 55% and 50% abnormalities, respectively. In Group B (VN), caloric, oVEMP and cVEMP tests revealed 100%, 80% and 45% abnormalities on the lesion ears, and 0%, 40% and 0% abnormalities on the healthy (opposite) ears, respectively. The 40% oVEMP abnormality on the healthy ears may be due to recording failure from the presence of spontaneous nystagmus, since five of five VN patients showed normal oVEMPs on the healthy ears, one year after presentation.
Presence of pathological eye movements may affect the recordings of oVEMP. Thus, the oVEMP test is recommended to perform after acute vertiginous episode to exclude the influence of pathological eye movements on the oVEMP recordings.
本研究调查了病理性眼动对视性前庭诱发肌源性电位（oVEMP）记录的影响。
将10例非前庭性起源的病理性眼动患者（9例先天性眼球震颤和1例眼阵挛）且MRI结果为阴性的患者分为A组。另外20例患有自发性眼球震颤的前庭神经炎（VN）患者分为B组。两组均接受听力测定、冷热试验、oVEMP和颈性VEMP（cVEMP）测试。
在A组中，冷热试验、oVEMP和cVEMP测试的异常率分别为40%、55%和50%。在B组（VN）中，冷热试验、oVEMP和cVEMP测试显示病变耳的异常率分别为100%、80%和45%，健侧（对侧）耳的异常率分别为0%、40%和0%。健侧耳40%的oVEMP异常可能是由于存在自发性眼球震颤导致记录失败，因为5例VN患者在发病1年后健侧耳的oVEMP均正常。
病理性眼动的存在可能会影响oVEMP的记录。因此，建议在急性眩晕发作后进行oVEMP测试，以排除病理性眼动对oVEMP记录的影响。
