Mergler Michaela, Driessen Martin, Lüdecke Christel, Ohlmeier Martin, Chodzinski Claudia, Weirich Steffen, Schläfke Detlef, Wedekind Dirk, Havemann-Reinecke Ursula, Renner Walter, Schäfer Ingo
a Psychologist , Alpen-Adria-Universitat Klagenfurt, Clinical Psychology , Klagenfurt , Austria.
b Professor , Clinic of Psychiatry and Psychotherapy Bethel , Bielefeld , Germany.
J Psychoactive Drugs. 2017 Jul-Aug;49(3):225-232. doi: 10.1080/02791072.2017.1296209. Epub 2017 Mar 21.
The increasing support for a dissociative subtype of post-traumatic stress disorder (PTSD-D) has led to its inclusion in DSM-5. We examined relationships between PTSD-D and relevant variables in patients with substance use disorders (SUD). The sample comprised N = 459 patients with SUD. The International Diagnostic Checklist and the Posttraumatic Diagnostic Scale were used to diagnose PTSD. In addition, participants completed the Childhood Trauma Questionnaire and the Dissociative Experiences Scale. The course of SUD was assessed by means of the European Addiction Severity Index. One-fourth of participants fulfilled a diagnosis of PTSD (25.3%). Patients with PTSD-D (N = 32, 27.6% of all patients with PTSD) reported significantly more current depressive symptoms, more current suicidal thoughts, more lifetime anxiety/tension, and more suicide attempts. The PTSD-D group also showed a significantly higher need for treatment due to drug problems, higher current use of opiates/analgesics, and a higher number of lifetime drug overdoses. In a regression model, symptoms of depression in the last month and lifetime suicide attempts significantly predicted PTSD-D. These findings suggest that PTSD-D is related to additional psychopathology and to a more severe course of substance-related problems in patients with SUD, indicating that this group also has additional treatment needs.
对创伤后应激障碍分离亚型(PTSD-D)越来越多的支持已使其被纳入《精神疾病诊断与统计手册》第五版(DSM-5)。我们研究了物质使用障碍(SUD)患者中PTSD-D与相关变量之间的关系。样本包括N = 459名SUD患者。使用国际诊断清单和创伤后诊断量表来诊断创伤后应激障碍。此外,参与者完成了儿童创伤问卷和分离体验量表。通过欧洲成瘾严重程度指数评估SUD的病程。四分之一的参与者符合创伤后应激障碍的诊断(25.3%)。PTSD-D患者(N = 32,占所有创伤后应激障碍患者的27.6%)报告当前的抑郁症状、当前的自杀念头、一生中的焦虑/紧张情绪以及自杀未遂情况明显更多。PTSD-D组由于药物问题显示出明显更高的治疗需求、当前更高的阿片类药物/镇痛药使用量以及一生中更高的药物过量次数。在一个回归模型中,过去一个月的抑郁症状和一生中的自杀未遂情况显著预测了PTSD-D。这些发现表明,PTSD-D与额外的精神病理学以及SUD患者中与物质相关问题的更严重病程相关,这表明该组患者也有额外的治疗需求。