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GEMINI-ACS-1: toward unearthing the antithrombotic therapy cornerstone for acute coronary syndromes.

作者信息

Gurbel Paul A, Tantry Udaya S

机构信息

Inova Center for Thrombosis Research and Drug Development, Inova Heart and Vascular Institute, Falls Church, VA 22042, USA; Johns Hopkins University School of Medicine, Baltimore, MD, USA; Duke University School of Medicine, Durham, NC, USA.

Inova Center for Thrombosis Research and Drug Development, Inova Heart and Vascular Institute, Falls Church, VA 22042, USA.

出版信息

Lancet. 2017 May 6;389(10081):1773-1775. doi: 10.1016/S0140-6736(17)30760-2. Epub 2017 Mar 18.

DOI:10.1016/S0140-6736(17)30760-2
PMID:28325639
Abstract
摘要

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GEMINI-ACS-1: toward unearthing the antithrombotic therapy cornerstone for acute coronary syndromes.GEMINI-ACS-1：探寻急性冠状动脉综合征的抗血栓治疗基石
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[After the GEMINI-ACS-1 trial].
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A randomized trial to compare the safety of rivaroxaban vs aspirin in addition to either clopidogrel or ticagrelor in acute coronary syndrome: The design of the GEMINI-ACS-1 phase II study.一项比较利伐沙班与阿司匹林联合氯吡格雷或替格瑞洛用于急性冠状动脉综合征安全性的随机试验：GEMINI-ACS-1 II期研究设计
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Reduction of stent thrombosis in patients with acute coronary syndromes treated with rivaroxaban in ATLAS-ACS 2 TIMI 51.在 ATLAS-ACS 2 TIMI 51 研究中，接受利伐沙班治疗的急性冠脉综合征患者中支架血栓形成减少。
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Antithrombotic treatment in acute coronary syndromes.急性冠脉综合征的抗血栓治疗。
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Effect of Rivaroxaban and Clopidogrel Combination Therapy on In-Stent Responses After Everolimus-Eluting Stent Implantation in a Porcine Coronary Model.依维莫司洗脱支架置入后猪冠状动脉模型中利伐沙班和氯吡格雷联合治疗对支架内反应的影响。
J Atheroscler Thromb. 2022 Jan 1;29(1):69-81. doi: 10.5551/jat.56549. Epub 2020 Nov 18.
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Clinical effects with inhibition of multiple coagulative pathways in patients admitted for acute coronary syndrome.急性冠脉综合征患者采用多靶点凝血途径抑制的临床效果。
Intern Emerg Med. 2018 Oct;13(7):1019-1028. doi: 10.1007/s11739-018-1834-x. Epub 2018 Mar 21.
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Evolving cardiovascular uses of direct-acting oral anticoagulants: a paradigm shift on the horizon?
直接作用的口服抗凝剂在心血管领域的应用进展：即将出现的范式转变？
Intern Emerg Med. 2017 Oct;12(7):923-934. doi: 10.1007/s11739-017-1724-7. Epub 2017 Aug 7.