Antoniolli Luciana, Borges Rafael, Goldani Luciano Z
Infectious Disease Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2350, 90640-000 Porto Alegre, RS, Brazil.
Case Rep Med. 2017;2017:4307468. doi: 10.1155/2017/4307468. Epub 2017 Feb 23.
Encephalitis and meningitis due to BKPyV are unusual and emerging condition. Only a few cases of BKPyV encephalitis have been reported in hematopoietic stem cell transplant recipients, with the majority of cases presenting with concurrent hemorrhagic cystitis and HIV-infected patients. The authors report two HIV-infected patients with the diagnosis of BKPyV encephalitis and discuss the main clinical, diagnostic, and therapeutic aspects of this infection in patients with AIDS. Physicians should be aware to recognize the main clinical features and diagnose BKPyV central nervous infection in the setting of AIDS.
由BK多瘤病毒(BKPyV)引起的脑炎和脑膜炎是一种罕见且新出现的病症。造血干细胞移植受者中仅报告了少数几例BKPyV脑炎病例,大多数病例同时伴有出血性膀胱炎,还有HIV感染患者。作者报告了两名被诊断为BKPyV脑炎的HIV感染患者,并讨论了艾滋病患者中这种感染的主要临床、诊断和治疗方面。医生应注意识别主要临床特征,并在艾滋病背景下诊断BKPyV中枢神经系统感染。