Opthof T, de Jonge B, Jongsma H J, Bouman L N
Department of Physiology, University of Amsterdam, The Netherlands.
J Mol Cell Cardiol. 1987 Dec;19(12):1221-36. doi: 10.1016/s0022-2828(87)80532-1.
The porcine sinoatrial node in an isolated right atrium preparation is characterized by unifocal impulse generation. It has a rather elongated shape and the larger part of its volume is taken up by collagen and fibroblasts. The impulse appears to emerge from a site where the percentage of myofilaments is relatively low. The impulse is propagated faster towards the crista terminalis than to the interatrial septum with preference for the oblique-upward direction. A very large zone of cells with low excitability is located at the interatrial septal side of the node.
在离体右心房标本中,猪的窦房结具有单灶性冲动产生的特征。它的形状相当细长,其大部分体积被胶原蛋白和成纤维细胞占据。冲动似乎起源于肌丝百分比相对较低的部位。冲动向界嵴的传播速度比对房间隔的传播速度更快,且更倾向于斜向上的方向。在窦房结的房间隔侧有一个非常大的低兴奋性细胞区域。