[用于预防和控制龋齿及牙周疾病的纳米药物递送系统的研究进展]
[Research progress on a nanodrug delivery system for prevention and control of dental caries and periodontal diseases].
作者信息
Yaling Jiang, Mingye Feng, Lei Cheng
机构信息
State Key Laboratory of Oral Diseases, Dept. of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
出版信息
Hua Xi Kou Qiang Yi Xue Za Zhi. 2017 Feb 1;35(1):104-107. doi: 10.7518/hxkq.2017.01.017.
Abstract
Dental caries and periodontal diseases are common chronic infectious diseases that cause serious damage to oral health. Bacteria is the primary factor leading to such conditions. As a dental plaque control method, chemotherapeutic agents face serious challenges in dental care because of the specific physiological and anatomical characteristics of the oral cavity. Nanodrug delivery system is a series of new drug delivery systems at nanoscale, and it can target cells, promote sustainedrelease effects, and enhance biodegradation. This review focuses on research progress on nanodrug delivery systems for prevention and control of dental caries and periodontal diseases.
摘要
龋齿和牙周疾病是常见的慢性感染性疾病，会对口腔健康造成严重损害。细菌是导致这些疾病的主要因素。作为一种牙菌斑控制方法，由于口腔特定的生理和解剖学特征，化学治疗剂在牙科护理中面临严峻挑战。纳米药物递送系统是一系列纳米级的新型药物递送系统，它可以靶向细胞、促进缓释效果并增强生物降解性。本文综述聚焦于纳米药物递送系统在预防和控制龋齿及牙周疾病方面的研究进展。
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