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超声描述的子宫内膜息肉患者的子宫内息肉及宫腔刮片的组织病理学评估。

Histopathological evaluation of intrauterine polyps and scrapings of the uterine cavity in women with endometrial polyp described in ultrasound.

作者信息

Radowicka Malgorzata, Legutowska Ewa, Gajewska Malgorzata, Wielgos Miroslaw

机构信息

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

Department of Obstetrics, Gynecology and Oncology, II Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland.

出版信息

Neuro Endocrinol Lett. 2016 Dec;37(7):518-522.

Abstract

OBJECTIVES

The aim of the study was to analyze the histopathology results of polyps removed and scrapings taken from the uterus in women, in whom ultrasound described endometrial polyp.

METHODS

The study included 412 patients whose ultrasound described endometrial polyp in the uterine cavity. The material obtained during hysteroscopy or curettage of the uterine cavity were subjected to the histological evaluation. The study group was divided into two subgroups depending on the presence of symptoms. The analysis of the relationship between variables was performed using Student's t-test and the Mann-Whitney U test.

RESULTS

In our study of 412 patients with suspected endometrial polyp based on ultrasound 342 patients had mild lesions in the uterine cavity, including a 51 of women had mild hyperplasia, 14 of women had endometrial hyperplasia with atypia or endometrial cancer. Subgroup of women who report abnormal bleeding accounted for 49.8% study group, asymptomatic patients was 50.2%.

CONCLUSIONS

This study showed no higher incidence of precancerous lesions and cancers of the endometrium in women with endometrial polyp described in ultrasound, who reported abnormal bleeding. Ultrasound-based diagnosis of endometrial polyps should therefore be verified both in women who report abnormal bleeding, as well as in asymptomatic women.

摘要

目的

本研究旨在分析超声检查显示存在子宫内膜息肉的女性患者切除的息肉及取自子宫的刮片的组织病理学结果。

方法

本研究纳入了412例超声检查显示子宫腔内存在子宫内膜息肉的患者。对宫腔镜检查或刮宫术获取的材料进行组织学评估。根据症状的有无,将研究组分为两个亚组。使用学生t检验和曼-惠特尼U检验对变量之间的关系进行分析。

结果

在我们对412例基于超声怀疑患有子宫内膜息肉的患者的研究中,342例患者子宫腔内有轻度病变,其中51例女性有轻度增生,14例女性有非典型子宫内膜增生或子宫内膜癌。报告有异常出血的女性亚组占研究组的49.8%,无症状患者占50.2%。

结论

本研究表明,超声检查显示存在子宫内膜息肉且报告有异常出血的女性,其子宫内膜癌前病变和癌症的发生率并未更高。因此,对于报告有异常出血的女性以及无症状女性,基于超声诊断的子宫内膜息肉均应进行核实。

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