Lin Jyh-Miin, Patterson Andrew J, Chao Tzu-Cheng, Zhu Chengcheng, Chang Hing-Chiu, Mendes Jason, Chung Hsiao-Wen, Gillard Jonathan H, Graves Martin J
Department of Radiology, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom. Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan.
Phys Med Biol. 2017 May 21;62(10):N204-N218. doi: 10.1088/1361-6560/aa685a. Epub 2017 Mar 22.
The paper reports a free-breathing black-blood CINE fast-spin echo (FSE) technique for measuring abdominal aortic wall motion. The free-breathing CINE FSE includes the following MR techniques: (1) variable-density sampling with fast iterative reconstruction; (2) inner-volume imaging; and (3) a blood-suppression preparation pulse. The proposed technique was evaluated in eight healthy subjects. The inner-volume imaging significantly reduced the intraluminal artifacts of respiratory motion (p = 0.015). The quantitative measurements were a diameter of 16.3 ± 2.8 mm and wall distensibility of 2.0 ± 0.4 mm (12.5 ± 3.4%) and 0.7 ± 0.3 mm (4.1 ± 1.0%) for the anterior and posterior walls, respectively. The cyclic cross-sectional distensibility was 35 ± 15% greater in the systolic phase than in the diastolic phase. In conclusion, we developed a feasible CINE FSE method to measure the motion of the abdominal aortic wall, which will enable clinical scientists to study the elasticity of the abdominal aorta.
该论文报道了一种用于测量腹主动脉壁运动的自由呼吸黑血电影快速自旋回波（FSE）技术。自由呼吸电影FSE包括以下磁共振技术：（1）采用快速迭代重建的可变密度采样；（2）容积内成像；以及（3）血液抑制准备脉冲。该技术在8名健康受试者身上进行了评估。容积内成像显著减少了呼吸运动的管腔内伪影（p = 0.015）。定量测量结果显示，前壁直径为16.3±2.8mm，壁扩张性为2.0±0.4mm（12.5±3.4%）；后壁直径为0.7±0.3mm（4.1±1.0%）。收缩期的周期性横截面扩张性比舒张期大35±15%。总之，我们开发了一种可行的电影FSE方法来测量腹主动脉壁的运动，这将使临床科学家能够研究腹主动脉的弹性。
