Upadhyay S K, Singh Pradhan P M, Mahato R K, Marasini B, Upadhyaya B, Shakya G, Baral G, Baral K P
Department of Community Health Sciences, Patan Academy of Health Sciences, Lalitpur, Nepal.
Epidemiology and Disease Control Division, Department of Health Services, Ministry of Health, Nepal.
J Nepal Health Res Counc. 2016 Sep;14(34):186-191.
An outbreak investigation study was conducted in Pajaru, one of the initially affected Village Development Committees (VDCs) of the Jajarkot district in Nepal following an outbreak of respiratory illness in early 2015. The objectives of this study were to identify the cases and magnitude of the outbreak.
A cross-sectional study was carried out in mid-April 2015 covering five most affected wards of Pajaru VDC to assess the patients using standard case definition for Influenza like Illness (ILI). Throat and nasal swabs were collected and sent to the National Influenza Center (NIC) in Kathmandu for laboratory confirmation.
The throat swab samples tested at NIC found Influenza A H1N1 pdm09. The attack rate was calculated to be 3% in ward number 9 and 41% in ward number 8. Wavelength of the infection was nearly two weeks in both the wards. Nearly 54% of the specimens were positive for Influenza A H1N1 pdm09. There was no ILI case fatality in the study area. Children aged 0-15 years were most affected. Majority of the patients presented with symptoms of fever, cough and sore throat.
There was gradual decline in the number of cases in all five wards suggestive of development of natural immunity in the community. True severity of the outbreak was not accurately reflected as compared to media reports.
2015年初尼泊尔贾尔贾科特地区最初受影响的村庄发展委员会(VDC)之一的帕贾鲁发生呼吸道疾病疫情后,开展了一项疫情调查研究。本研究的目的是确定疫情的病例和规模。
2015年4月中旬在帕贾鲁村庄发展委员会五个受影响最严重的选区进行了一项横断面研究,以使用流感样疾病(ILI)的标准病例定义评估患者。采集咽喉和鼻拭子并送往加德满都的国家流感中心(NIC)进行实验室确认。
在国家流感中心检测的咽喉拭子样本中发现甲型H1N1 pdm09流感病毒。第9选区的发病率经计算为3%,第8选区为41%。两个选区的感染周期均接近两周。近54%的标本对甲型H1N1 pdm09流感病毒呈阳性。研究区域内没有流感样疾病病例死亡。0至15岁的儿童受影响最大。大多数患者出现发热咳嗽和喉咙痛症状。
所有五个选区的病例数都在逐渐下降,这表明社区中产生了自然免疫力。与媒体报道相比,此次疫情的实际严重程度没有得到准确反映。