Chan J K, Ng W F
Institute of Pathology, Queen Elizabeth Hospital, Hong Kong.
Pathology. 1987 Oct;19(4):425-8. doi: 10.3109/00313028709103896.
Sclerosing adenosis is a common proliferative lesion of the mammary lobule which is not associated with an increased risk of developing breast cancer. An unusual case of florid sclerosing adenosis showing extensive cancerization by intraductal carcinoma is reported. The neoplastic nature of the sclerosing lesion can be recognized by the unusual distension of the tubules by cells and the subtle cytological changes, and further confirmed by finding foci of classical intraductal carcinoma.
硬化性腺病是乳腺小叶常见的增殖性病变，与患乳腺癌风险增加无关。本文报告了一例罕见的 florid 硬化性腺病病例，其显示出导管内癌广泛癌变。硬化性病变的肿瘤性质可通过细胞导致的小管异常扩张和细微的细胞学变化来识别，并通过发现典型导管内癌灶进一步确诊。
