Gershon P D, Knowles N J
AFRC Institute for Animal Health, Woking, Surrey, UK.
Nucleic Acids Res. 1988 Mar 11;16(5):1779-87. doi: 10.1093/nar/16.5.1779.
A program is described which aligns pairs of linear restriction site maps using an algorithm which maximizes the number of coincident sites through the addition of extra 'padding' fragments; and makes maps of the non-conserved sites between pairs and triplets of input maps. A range of display facilities, hardcopy functions and database management routines are also included. The program runs on a stand-alone microcomputer, and is stored along with a database of several hundred files on a single floppy disc.
本文描述了一个程序,该程序使用一种算法来比对线性限制酶切位点图谱对,该算法通过添加额外的“填充”片段来最大化重合位点的数量;并绘制输入图谱对和三联体之间非保守位点的图谱。还包括一系列显示工具、硬拷贝功能和数据库管理程序。该程序在独立的微型计算机上运行,并与数百个文件的数据库一起存储在一张软盘上。