Martin Brent C, Thomas Logan W, Dann Francis J
Department of Dermatology, University of California, Irvine.
Dermatol Online J. 2017 Feb 15;23(2):13030/qt36n2k4jw.
Psoriatic arthritis (PsA) is a chronic inflammatoryarthropathy that affects joints and entheses andis associated with psoriasis (PsO). There are fiveclinical patterns of PsA: symmetrical polyarthritis,distal interphalangeal arthropathy, asymmetricaloligoarthritis, arthritis mutilans, and spondylitis, withor without sacroiliitis. Concerning PsA, the goals oftherapy are to control inflammation, prevent articulardamage, and reduce discomfort in the affected joints.Although there are many therapeutic options forthe treatment of PsAs, physicians most often beginwith nonsteroidal anti-inflammatory drugs (NSAIDs)for mild disease. Disease-modifying anti-rheumaticdrugs (DMARDS) are reserved for moderate to severedisease. Apremilast may be a useful option for somepatients.
银屑病关节炎（PsA）是一种慢性炎症性关节病，会影响关节和附着点，并与银屑病（PsO）相关。PsA有五种临床类型：对称性多关节炎、远端指间关节病、非对称性少关节炎、残毁性关节炎和脊柱炎，伴或不伴骶髂关节炎。关于PsA，治疗目标是控制炎症、预防关节损伤并减轻受累关节的不适。虽然治疗PsA有很多治疗选择，但医生通常首先用非甾体抗炎药（NSAIDs）治疗轻症。改善病情抗风湿药（DMARDs）则用于中至重度疾病。阿普司特对某些患者可能是一种有用的选择。
