姿势对健康受试者QT间期心脏去极化和复极化阶段的影响。
The impact of posture on the cardiac depolarization and repolarization phases of the QT interval in healthy subjects.
作者信息
Obata Yurie, Ruzankin Pavel, Ong Qi Jia, Berkowitz Dan E, Berger Ronald D, Steppan Jochen, Barodka Viachaslau
机构信息
Division of Cardiac Anesthesia, Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Sobolev Institute of Mathematics, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, Russia.
出版信息
J Electrocardiol. 2017 Sep-Oct;50(5):640-645. doi: 10.1016/j.jelectrocard.2017.03.001. Epub 2017 Mar 12.
BACKGROUND
Postural changes affect both heart rate and the QT interval.
OBJECTIVE
To investigate the effects of postural changes on the depolarization and repolarization phases of the QT interval.
METHODS
A three lead ECG from 12 healthy young volunteers was recorded in the standing, sitting and in the supine positions. For the purpose of this study, we defined the depolarization phase as the QRS complex plus the ST segment and the repolarization phase as the duration of the T wave.
RESULTS
QTc did not change with changes in position. The ratio of the duration of the depolarization phase to the repolarization phase was higher in the supine position (0.98±0.13) compared to the standing position (0.83±0.17).
CONCLUSIONS
The origin of the T wave moves closer to the QRS complex during standing compared to the supine position. The observed changes are mainly due to shortening of the ST segment during standing compared to supine position.
背景
姿势变化会影响心率和QT间期。
目的
研究姿势变化对QT间期去极化和复极化阶段的影响。
方法
记录12名健康年轻志愿者在站立、坐着和仰卧位时的三导联心电图。在本研究中，我们将去极化阶段定义为QRS波群加ST段，将复极化阶段定义为T波持续时间。
结果
QTc不随体位变化而改变。与站立位（0.83±0.17）相比，仰卧位去极化阶段与复极化阶段持续时间的比值更高（0.98±0.13）。
结论
与仰卧位相比，站立时T波的起点更靠近QRS波群。观察到的变化主要是由于站立时与仰卧位相比ST段缩短。
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