Sodium Channel β Subunits in Epilepsy: Location, Location, Location.
作者信息
Kearney Jennifer A
出版信息
Epilepsy Curr. 2017 Jan-Feb;17(1):52-53. doi: 10.5698/1535-7511-17.1.52.
Abstract
摘要
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J Neurosci. 2016 Jun 8;36(23):6213-24. doi: 10.1523/JNEUROSCI.0405-16.2016.
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Structure-based site-directed photo-crosslinking analyses of multimeric cell-adhesive interactions of voltage-gated sodium channel β subunits.
Sci Rep. 2016 May 24;6:26618. doi: 10.1038/srep26618.
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Annu Rev Physiol. 2015;77:481-504. doi: 10.1146/annurev-physiol-021014-071846.
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Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain.
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Enhanced in vitro CA1 network activity in a sodium channel β1(C121W) subunit model of genetic epilepsy.
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Functional modulation of voltage-dependent sodium channel expression by wild type and mutated C121W-β1 subunit.
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Modulation of sodium current in mammalian cells by an epilepsy-correlated beta 1-subunit mutation.
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