Acar Turan, Atahan Murat Kemal, Çelik Salih Can, Yemez Kürşat, Ülker Gülden Ballı, Yiğit Seyran, Tarcan Ercüment
Clinic of General Surgery, İzmir Katip Çelebi University Atatürk Training and Research Hospital, İzmir, Turkey.
Clinic of Pathology, İzmir Katip Çelebi University, Atatürk Training and Research Hospital, İzmir, Turkey.
J Breast Health. 2014 Oct 1;10(4):245-247. doi: 10.5152/tjbh.2014.1931. eCollection 2014 Oct.
Adenoid cystic carcinoma of the breast constitutes approximately 0.1% of all breast tumors. They can be located in the trachea, bronchus, cervix, lacrimal gland, and skin as well as the breast. Tumors in the breast have better prognoses compared to those in other locations. The diagnosis and treatment planning of this tumor is challenging due to its rare incidence. In this article, we presented a case that was diagnosed with adenoid cystic carcinoma of the breast upon pathology evaluation. A 59-year-old female patient was admitted to our clinic due to a mass in her right breast. Her mammography revealed a 1 cm in diameter mass in the upper outer quadrant of the right breast, which was classified as BIRADS 4C (Breast Imaging Reporting and Data System). On magnetic resonance imaging (MRI) the lesion was also reported as BIRADS 4C. The patient underwent breast conserving surgery (BCS), and the pathology result was reported as adenoid cystic carcinoma of the breast. The patient received chemo-radiotherapy in the postoperative period. Adenoid cystic carcinoma of the breast has been first described in the salivary glands. They can be confused with benign lesions both on physical and radiological examinations. Sentinel lymph node biopsy (SLNB) can be used since axillary metastases are rare. Local recurrence and distant metastases are also very rare. Usually, BCS followed by radiotherapy is adequate to obtain local control. In selected patients with a poor prognosis, chemotherapy and hormonal therapy should be added to the treatment.
乳腺腺样囊性癌约占所有乳腺肿瘤的0.1%。它们可发生于气管、支气管、宫颈、泪腺、皮肤以及乳腺。与其他部位的肿瘤相比，乳腺肿瘤的预后较好。由于其发病率低，该肿瘤的诊断和治疗规划具有挑战性。在本文中，我们介绍了一例经病理评估诊断为乳腺腺样囊性癌的病例。一名59岁女性患者因右乳肿块入住我院。她的乳腺钼靶检查显示右乳外上象限有一个直径1厘米的肿块，分类为乳腺影像报告和数据系统（BIRADS）4C级。磁共振成像（MRI）检查该病变也报告为BIRADS 4C级。患者接受了保乳手术（BCS），病理结果报告为乳腺腺样囊性癌。患者术后接受了放化疗。乳腺腺样囊性癌最早在涎腺中被描述。在体格检查和影像学检查中，它们都可能与良性病变相混淆。由于腋窝转移罕见，可采用前哨淋巴结活检（SLNB）。局部复发和远处转移也非常罕见。通常，保乳手术加放疗足以实现局部控制。对于预后较差的特定患者，治疗中应加用化疗和激素治疗。
