İlhan Enver, Üreyen Orhan, Şenlikci Abdullah, Yağcı Ayşe, Yeldan Eyüp, Salman Tarık, Tekeli Mehmet Tahsin
Clinic of General Surgery, İzmir Training and Research Hospital, İzmir, Turkey.
Clinic of Pathology, İzmir Bozyaka Training and Research Hospital, İzmir, Turkey.
J Breast Health. 2015 Jan 1;11(1):45-47. doi: 10.5152/tjbh.2014.2006. eCollection 2015 Jan.
Intracystic papillary carcinoma of the breast (IPC) is usually seen in postmenopausal elderly women. Its prognosis is much better than other type of breast tumors, and usually do not contain invasive components. Surgical excision with negative margins and axillary sentinel lymph node sampling is the recommended treatment. Two cases of intracystic papillary carcinoma of the breast that was treated at our clinic are herein presented. Both cases were postmenopausal, were both positive for estrogen and progesterone receptors and negative for HER 2. They underwent breast-conserving surgery. One patient had an invasive focus, therefore axillary lymph node sampling was performed, and the sentinel lymph node was not metastatic. This patient received hormonal therapy as well as radiotherapy. In the other case, there was no invasive focus and the surgical margins were negative, therefore, additional surgery was not performed. The patient is receiving hormonal therapy. Intracystic carcinoma of the breast should be kept in mind especially in elderly patients with breast cysts, with clinically or radiologically suspicious features, and biopsy and local excision should be considered. Although there is not any standard approach for patients with IPC, each patient must be evaluated for surgery and should be individually assessed in terms of adjuvant therapy.
乳腺囊内乳头状癌(IPC)通常见于绝经后老年女性。其预后远优于其他类型的乳腺肿瘤,且通常不包含浸润成分。推荐的治疗方法是进行切缘阴性的手术切除及腋窝前哨淋巴结取样。本文介绍了在我们诊所接受治疗的两例乳腺囊内乳头状癌病例。两例均为绝经后患者,雌激素和孕激素受体均呈阳性,HER 2呈阴性。她们均接受了保乳手术。其中一名患者有浸润灶,因此进行了腋窝淋巴结取样,前哨淋巴结无转移。该患者接受了激素治疗及放疗。另一例患者没有浸润灶,手术切缘阴性,因此未进行额外手术。该患者正在接受激素治疗。对于有乳腺囊肿、具有临床或放射学可疑特征的老年患者,尤其应考虑到乳腺囊内癌,应考虑进行活检和局部切除。尽管对于IPC患者没有任何标准治疗方法,但必须对每位患者进行手术评估,并应根据辅助治疗进行个体化评估。