伴有多灶性传导阻滞的近端慢性炎性多发性神经病

Proximal chronic inflammatory polyneuropathy with multifocal conduction block.

作者信息

Bradley W G, Bennett R K, Good P, Little B

机构信息

Department of Neurology, University of Vermont College of Medicine, Burlington.

出版信息

Arch Neurol. 1988 Apr;45(4):451-5. doi: 10.1001/archneur.1988.00520280101025.

DOI:10.1001/archneur.1988.00520280101025

PMID:2833207

Abstract

The pathological findings in proximal and distal nerve biopsy specimens are described in a patient with the clinical and electrophysiological features of chronic inflammatory polyneuropathy with multifocal conduction block. Proximal onion bulb hypertrophic changes in the brachial plexus were associated with inflammatory cell infiltrates. In contrast, the sural nerve biopsy specimen showed a mild picture of mixed axonal degeneration and demyelination-remyelination without inflammatory infiltration.

摘要

一名患有慢性炎症性多发性神经病伴多灶性传导阻滞临床及电生理特征的患者，其近端和远端神经活检标本的病理结果如下所述。臂丛神经近端的洋葱球样肥大改变与炎性细胞浸润相关。相比之下，腓肠神经活检标本显示为轻度的混合性轴索性变性及脱髓鞘 - 再髓鞘化表现，无炎性浸润。