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经导管主动脉瓣置换术和外科主动脉瓣置换术后心肌变形的变化。

Changes in myocardial deformation after transcatheter and surgical aortic valve replacement.

作者信息

Garg Vinisha, Ho Jonathan K, Vorobiof Gabriel

机构信息

Department of Medicine, Division of Cardiology, David Geffen School of Medicine at UCLA, Ronald Reagan UCLA Medical Center, Los Angeles, CA, USA.

Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine at UCLA, Ronald Reagan UCLA Medical Center, Los Angeles, CA, USA.

出版信息

Echocardiography. 2017 Apr;34(4):603-613. doi: 10.1111/echo.13485. Epub 2017 Mar 23.

Abstract

Speckle tracking echocardiography (STE) has emerged as a novel angle-independent modality in assessing myocardial velocity, deformation, and strain. Its role in assessing change before and after aortic valve replacement in patients with aortic stenosis (AS) has recently generated interest. This review summarizes the practical utility and clinical implications of myocardial deformation by STE after surgical or transcatheter aortic valve replacement (TAVR). Overall, atrial strain and ventricular strain as measured by STE improve after surgical and transcatheter aortic intervention in short- and long-term follow-up with evidence of a more pronounced acute improvement in patients who undergo TAVR. STE assessment of strain, particularly global longitudinal strain, can detect subtle changes in myocardial systolic function prior to conventional variables such as left ventricular ejection fraction and is clinically useful in predicting mortality and symptom development in patients with AS. This underscores the emerging role of STE in monitoring post-procedural improvements in cardiac function as well as the potential value in guiding optimal timing of AS intervention.

摘要

斑点追踪超声心动图(STE)已成为一种新型的、与角度无关的评估心肌速度、变形和应变的方法。其在评估主动脉瓣狭窄(AS)患者主动脉瓣置换前后变化中的作用最近引起了关注。本综述总结了外科或经导管主动脉瓣置换术(TAVR)后STE评估心肌变形的实际应用和临床意义。总体而言,STE测量的心房应变和心室应变在外科和经导管主动脉干预后的短期和长期随访中均有改善,证据表明接受TAVR的患者急性改善更为明显。STE对应变的评估,尤其是整体纵向应变,可在左心室射血分数等传统变量之前检测到心肌收缩功能的细微变化,并且在预测AS患者的死亡率和症状发展方面具有临床实用性。这突出了STE在监测术后心脏功能改善方面的新兴作用以及在指导AS干预最佳时机方面的潜在价值。

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