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“颈部的APAAN”——对爱尔兰在常规法医分析期间在查获的含苯丙胺材料中发现的一些新型杂质的思考。

'APAAN in the neck' - A reflection on some novel impurities found in seized materials containing amphetamine in Ireland during routine forensic analysis.

作者信息

Power John D, Kavanagh Pierce, McLaughlin Gavin, Barry Michael, Dowling Geraldine, Brandt Simon D

机构信息

Department of Pharmacology and Therapeutics, School of Medicine, Trinity Centre for Health Sciences, St. James's Hospital, James's Street, Dublin 8, D08W9RT, Ireland.

Forensic Science Ireland, Garda HQ, Phoenix Park, Dublin 8, D08HN3X, Ireland.

出版信息

Drug Test Anal. 2017 Jul;9(7):966-976. doi: 10.1002/dta.2194. Epub 2017 May 10.

DOI:10.1002/dta.2194
PMID:28332334
Abstract

This perspective examines amphetamine importations into Ireland. Some novel by-products were detected and linked to a change in the method of production of P2P from APAAN. These by-products remained present during subsequent Leuckart reaction conditions. Novel by-products from substituted cathinone synthesis reactions were also isolated and characterized.

摘要

这篇透视文章研究了安非他明流入爱尔兰的情况。检测到了一些新的副产物,并将其与从APAAN生产苯基-2-丙酮的方法变化联系起来。在随后的柳卡特反应条件下,这些副产物仍然存在。还分离并表征了取代卡西酮合成反应产生的新副产物。

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'APAAN in the neck' - A reflection on some novel impurities found in seized materials containing amphetamine in Ireland during routine forensic analysis.“颈部的APAAN”——对爱尔兰在常规法医分析期间在查获的含苯丙胺材料中发现的一些新型杂质的思考。
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The identification of an impurity product, 4,6-dimethyl-3,5-diphenylpyridin-2-one in an amphetamine importation seizure, a potential route specific by-product for amphetamine synthesized by the APAAN to P2P, Leuckart route.在一次苯丙胺进口缉获行动中鉴定出一种杂质产物4,6-二甲基-3,5-二苯基吡啶-2-酮,这是通过从苯丙酮到苯基-2-丙酮的APAAN法、洛伊卡特法合成苯丙胺时一种可能的特定路线副产物。
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