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配药基础:配制薄膜。

Basics of Compounding: Compounding Films.

作者信息

Allen Loyd V

机构信息

International Journal of Pharmaceutical Compounding.

出版信息

Int J Pharm Compd. 2016 Jul-Aug;20(4):298-305.

Abstract

Films, which are a dosage form designed to dissolve on contact with a wet surface within a very short time, are thin sheets placed in the oral cavity for dissolution and absorption of the active drug. This dosage form is gaining popularity because of its convenience. Discussed within this article are the applications, advantages/disadvantages, composition, preparation, physicochemical considerations, quality control, packaging/labeling/storage, stability, and formulation considerations as they relate to films. Also provided are example formulations for compounding.

摘要

薄膜剂是一种设计用于在与湿润表面接触时能在极短时间内溶解的剂型,它是置于口腔中用于活性药物溶解和吸收的薄片。这种剂型因其便利性而越来越受欢迎。本文讨论了与薄膜剂相关的应用、优缺点、组成、制备、物理化学考量、质量控制、包装/标签/储存、稳定性以及制剂考量。还提供了用于配制的示例制剂。

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