Abu-El-Haija Maisam, Kumar Soma, Szabo Flora, Werlin Steven, Conwell Darwin, Banks Peter, Morinville Veronique D
*Division of Gastroenterology Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH †Division of Pediatric Gastroenterology, Hepatology and Nutrition, Rady Children's Hospital, San Diego, CA ‡Division of Pediatric Gastroenterology and Nutrition, Children's Hospital of Richmond at VCU, Virginia Commonwealth University School of Medicine, Richmond, VA §Medical College of Wisconsin, Milwaukee, WI ||Division of Gastroenterology, Hepatology and Nutrition, Ohio State University, Columbus, OH ¶Division of Gastroenterolology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA #Division of Pediatric Gastroenterology and Nutrition, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
J Pediatr Gastroenterol Nutr. 2017 Jun;64(6):984-990. doi: 10.1097/MPG.0000000000001583.
Acute pancreatitis (AP) is an emerging problem in pediatrics, with most cases resolving spontaneously. Approximately 10% to 30%, however, are believed to develop "severe acute pancreatitis" (SAP).
This consensus statement on the classification of AP in pediatrics was developed through a working group that performed an evidence-based search for classification of AP in adult pancreatitis, definitions and criteria of systemic inflammatory response syndrome, and organ failure in pediatrics.
Severity in pediatric AP is classified as mild, moderately severe, or severe. Mild AP is defined by AP without organ failure, local or systemic complications, and usually resolves in the first week. Moderately SAP is defined by the presence of transient organ failure that resolves in no >48 hours, or local complications or exacerbation of co-morbid disease. SAP is defined by persistent organ failure that lasts <48 hours. The presence of systemic inflammatory response syndrome is associated with increased risk for persistent organ dysfunction. Criteria to define organ failure must be pediatric- and age-based.
Classifying AP in pediatrics in a uniform fashion will help define outcomes and encourage the development of future studies in the field of pediatric pancreatitis.
急性胰腺炎（AP）在儿科领域是一个新出现的问题，大多数病例可自发缓解。然而，据信约10%至30%的病例会发展为“重症急性胰腺炎”（SAP）。
关于儿科AP分类的这一共识声明由一个工作组制定，该工作组对成人胰腺炎中AP的分类、全身炎症反应综合征的定义和标准以及儿科器官衰竭进行了循证检索。
儿科AP的严重程度分为轻度、中度严重或重度。轻度AP定义为无器官衰竭、局部或全身并发症的AP，通常在第一周内缓解。中度SAP定义为存在持续时间不超过48小时的短暂器官衰竭，或局部并发症或合并疾病加重。SAP定义为持续时间小于48小时的持续性器官衰竭。全身炎症反应综合征的存在与持续性器官功能障碍风险增加相关。定义器官衰竭的标准必须基于儿科和年龄。
以统一方式对儿科AP进行分类将有助于明确预后，并鼓励儿科胰腺炎领域未来研究的开展。
