Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Retina. 2018 Apr;38(4):684-691. doi: 10.1097/IAE.0000000000001588.
To investigate changes in metamorphopsia after rhegmatogenous retinal detachment surgery and to evaluate the relationship between metamorphopsia and retinal microstructures assessed with optical coherence tomography.
The study included 47 eyes of 47 patients undergoing retinal detachment surgery. We examined the severity of metamorphopsia using M-CHARTS, best-corrected visual acuity, and optical coherence tomography images. All data were recorded before and 3, 6, and 12 months after surgery, except for M-CHARTS which were recorded only postoperatively.
Metamorphopsia scores at 3, 6, and 12 months postoperatively were 0.46 ± 0.51, 0.41 ± 0.44, and 0.28 ± 0.37, respectively, with significant improvement from 3 months to 12 months after surgery. Significant metamorphopsia (score ≥0.2) was present in 49% of patients at 12 months postoperatively. Multiple regression analysis revealed that metamorphopsia score at 12 months was significantly related to the status of macula and interdigitation zone. In patients with macula-off retinal detachment, improvement of metamorphopsia scores was associated with an increase in thickness of external limiting membrane-retinal pigment epithelium.
After successful retinal detachment surgery, metamorphopsia gradually improved, but nearly half of the patients still exhibited metamorphopsia at 12 months postoperatively. Disruption of interdigitation zone and external limiting membrane-retinal pigment epithelium thickness was related to metamorphopsia.
研究孔源性视网膜脱离手术后的形觉扭曲变化,并评估光学相干断层扫描评估的视网膜微结构与形觉扭曲之间的关系。
本研究纳入 47 例(47 只眼)行视网膜脱离复位手术的患者。我们使用 M-CHARTS 检查、最佳矫正视力和光学相干断层扫描图像来评估形觉扭曲的严重程度。所有数据均在术前和术后 3、6 和 12 个月记录,除 M-CHARTS 仅在术后记录。
术后 3、6 和 12 个月的形觉扭曲评分分别为 0.46±0.51、0.41±0.44 和 0.28±0.37,术后 12 个月与术后 3 个月相比有显著改善。术后 12 个月,49%的患者存在明显的形觉扭曲(评分≥0.2)。多元回归分析显示,术后 12 个月的形觉扭曲评分与黄斑和内界膜交织区的状态显著相关。在黄斑脱离的视网膜脱离患者中,形觉扭曲评分的改善与外节膜-视网膜色素上皮厚度的增加有关。
成功的视网膜脱离手术后,形觉扭曲逐渐改善,但近一半的患者在术后 12 个月仍存在形觉扭曲。内界膜交织区和外节膜-视网膜色素上皮厚度的破坏与形觉扭曲有关。