Mandal Anirban, Priyadarshi Mayank, Jat Kanaram, Kabra Sushil Kumar
Department of Pediatrics, Sitaram Bhartia Institute of Science and Research, New Delhi 110016, India.
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi 110029, India.
J Trop Pediatr. 2017 Aug 1;63(4):328-332. doi: 10.1093/tropej/fmx003.
Cystic fibrosis (CF), an autosomal recessive disease with multi-system involvement, may present with bleeding in infancy owing to vitamin K malabsorption. Infantile tremor syndrome (ITS) is an obscure condition associated with vitamin B12 and other micronutrient deficiencies, described predominantly in Indian subcontinent. We describe an infant presenting with ITS and chronic subdural hemorrhage. He was subsequently diagnosed to have CF. The ITS and subdural hemorrhage is rarely reported in children with CF. In the background of increasing recognition of CF in Indian children, this case demonstrates a new association of this disease.
囊性纤维化（CF）是一种常染色体隐性疾病，可累及多系统，由于维生素K吸收不良，在婴儿期可能出现出血症状。婴儿震颤综合征（ITS）是一种与维生素B12及其他微量营养素缺乏相关的不明病症，主要在印度次大陆有相关描述。我们报告了一名患有ITS并伴有慢性硬膜下出血的婴儿。随后他被诊断为患有CF。CF患儿中很少有关于ITS和硬膜下出血的报道。鉴于印度儿童中对CF的认识日益增加，该病例展示了这种疾病的一种新关联。
