Feiglin B, Reade P C
Oral Surg Oral Med Oral Pathol. 1979 Mar;47(3):277-81. doi: 10.1016/0030-4220(79)90154-3.
The distribution of [14C] leucine and 85Sr labeled tracer microspheres from rat incisor pulp canals was investigated in an effort to establish the potential for passage of substances from within the root canal to the systemic circulation. Following introduction of the tracer materials into the pulp canals, the radioactivity in the lungs, spleen, kidney, liver, heart, blood, skeletal muscle, adrenal glands, salivary glands, and submandibular lymph nodes was determined. At all of the time intervals studied the incorporation of [14C] leucine into the adrenal gland was significantly greater than the [14C] leucine incorporation into the other organs. High levels of 85Sr labeled microspheres were detected in the ipsilateral submandibular glands and submandibular lymph nodes and in the lungs.
为了确定根管内物质进入体循环的可能性，对大鼠切牙髓管中[14C]亮氨酸和85Sr标记的示踪微球的分布进行了研究。将示踪物质引入牙髓管后，测定了肺、脾、肾、肝、心、血、骨骼肌、肾上腺、唾液腺和下颌下淋巴结中的放射性。在所有研究的时间间隔内，肾上腺中[14C]亮氨酸的掺入量显著高于其他器官中[14C]亮氨酸的掺入量。在同侧下颌下腺、下颌下淋巴结和肺中检测到高水平的85Sr标记微球。
