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法国大都市地区成人感染性脑炎的管理

Management of adult infectious encephalitis in metropolitan France.

作者信息

Goulenok T, Buzelé R, Duval X, Bruneel F, Stahl J P, Fantin B

机构信息

Service de médecine interne, hôpital Bichat-Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France.

Service de médecine interne, centre hospitalier de Saint-Brieuc, 10, rue Marcel-Proust, 22000 Saint-Brieuc, France.

出版信息

Med Mal Infect. 2017 May;47(3):206-220. doi: 10.1016/j.medmal.2017.01.006. Epub 2017 Mar 20.

DOI:10.1016/j.medmal.2017.01.006
PMID:28336304
Abstract

Infectious encephalitis is a severe disease leading to a high mortality and morbidity. The most frequent causes include Herpes simplex virus, Varicella Zoster virus, Listeria monocytogenes, and Mycobacterium tuberculosis. Urgent treatment is required (anti-infective therapy and nonspecific supportive care). The aim of this study was to define treatment strategy, empirical and after microbiological documentation at 48hours, through a systematic literature review.

摘要

感染性脑炎是一种导致高死亡率和高发病率的严重疾病。最常见的病因包括单纯疱疹病毒、水痘带状疱疹病毒、单核细胞增生李斯特菌和结核分枝杆菌。需要进行紧急治疗(抗感染治疗和非特异性支持治疗)。本研究的目的是通过系统的文献综述来确定治疗策略,包括48小时时的经验性治疗和微生物学确诊后的治疗。

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