[脊髓灰质炎病毒神经毒力和减毒的遗传决定因素]
[Genetic determinants of neurovirulence and attenuation of poliovirus].
作者信息
Azol V I
出版信息
Mol Gen Mikrobiol Virusol. 1988 Jan(1):3-9.
PMID:2833691
Abstract
The results of mapping of genetic determinants for poliovirus attenuation are reviewed. Possible mechanisms of the phenotypic expression of attenuating mutations located in different regions of the viral genome are discussed.
摘要
本文综述了脊髓灰质炎病毒减毒遗传决定因素的定位结果。讨论了位于病毒基因组不同区域的减毒突变表型表达的可能机制。
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