Lewis Daniel J, Duvic Madeleine
School of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas.
Department of Dermatology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1452, Pickens 411, Houston, Texas.
Dermatol Ther. 2017 May;30(3). doi: 10.1111/dth.12485. Epub 2017 Mar 24.
Extracorporeal photopheresis (ECP) has been used for nearly 30 years in the treatment of cutaneous T-cell lymphoma. However, current clinical practice largely reserves ECP for patients with late-stage mycosis fungoides (MF) or Sézary syndrome or for those who are refractory to other therapies. We briefly describe a 48-year-old male who experienced long-term complete remission of his patch MF disease with ECP, and we suggest a role for ECP in the treatment of early-stage MF given evidence of its efficacy, safety, and tolerability.
体外光化学疗法（ECP）已用于治疗皮肤T细胞淋巴瘤近30年。然而，目前的临床实践主要将ECP用于晚期蕈样肉芽肿（MF）或塞扎里综合征患者，或用于对其他疗法难治的患者。我们简要描述了一名48岁男性，他通过ECP实现了斑块状MF疾病的长期完全缓解，并且鉴于ECP的有效性、安全性和耐受性证据，我们认为ECP在早期MF治疗中具有一定作用。
