面部湿巾中的过敏原成分。

Allergenic Ingredients in Facial Wet Wipes.

机构信息

From the *University of Minnesota School of Medicine, Minneapolis; †Department of Dermatology, Minneapolis Veterans Affairs Medical Center, MN; ‡HCMC Parkside Occupational and Contact Dermatitis Clinic; and §Department of Dermatology, University of Minnesota, Minneapolis.

出版信息

Dermatitis. 2017 Nov/Dec;28(6):353-359. doi: 10.1097/DER.0000000000000268.

DOI:10.1097/DER.0000000000000268

PMID:28338538

Abstract

BACKGROUND

Allergic contact dermatitis commonly occurs on the face. Facial cleansing wipes may be an underrecognized source of allergens.

OBJECTIVE

The aim of this study was to determine the frequency of potentially allergenic ingredients in facial wet wipes.

METHODS

Ingredient lists from name brand and generic facial wipes from 4 large retailers were analyzed.

RESULTS

In the 178 facial wipes examined, a total of 485 ingredients were identified (average, 16.7 ingredients per wipe). Excluding botanicals, the top 15 potentially allergenic ingredients were glycerin (64.0%), fragrance (63.5%), phenoxyethanol (53.9%), citric acid (51.1%), disodium EDTA (44.4%), sorbic acid derivatives (39.3%), tocopherol derivatives (38.8%), polyethylene glycol derivatives (32.6%), glyceryl stearate (31.5%), sodium citrate (29.8%), glucosides (27.5%), cetearyl alcohol (25.8%), propylene glycol (25.3%), sodium benzoate (24.2%), and ceteareth-20 (23.6%)/parabens (23.6%). Of note, methylisothiazolinone (2.2%) and methylchloroisothiazolinone (1.1%) were uncommon. The top potential allergens of botanical origin included Aloe barbadensis (41.0%), chamomile extracts (27.0%), tea extracts (21.3%), Cucumis sativus (20.2%), and Hamamelis virginiana (10.7%).

CONCLUSIONS

Many potential allergens are present in facial wet wipes, including fragrances, preservatives, botanicals, glucosides, and propylene glycol.

摘要

背景

变应性接触性皮炎常发生于面部。面部清洁湿巾可能是过敏原的一个被低估的来源。

目的

本研究旨在确定面部湿巾中潜在过敏原成分的频率。

方法

分析了来自 4 家大型零售商的名牌和通用面部湿巾的成分清单。

结果

在检查的 178 片面部湿巾中，共鉴定出 485 种成分（平均每片湿巾 16.7 种成分）。不包括植物提取物，前 15 种潜在过敏原成分分别为甘油（64.0%）、香料（63.5%）、苯氧乙醇（53.9%）、柠檬酸（51.1%）、二钠 EDTA（44.4%）、山梨酸衍生物（39.3%）、生育酚衍生物（38.8%）、聚乙二醇衍生物（32.6%）、硬脂酸甘油酯（31.5%）、柠檬酸钠（29.8%）、糖苷（27.5%）、鲸蜡硬脂醇（25.8%）、丙二醇（25.3%）、苯甲酸钠（24.2%）和鲸蜡硬脂醇聚醚-20/对羟基苯甲酸酯（23.6%）。值得注意的是，甲基异噻唑啉酮（2.2%）和甲基氯异噻唑啉酮（1.1%）不常见。植物源的潜在过敏原包括库拉索芦荟（41.0%）、洋甘菊提取物（27.0%）、茶提取物（21.3%）、黄瓜（20.2%）和金缕梅（10.7%）。