From the *University of Minnesota School of Medicine; †Department of Dermatology, Minneapolis Veterans Affairs Medical Center; ‡HCMC Parkside Occupational and Contact Dermatitis Clinic; and §Department of Dermatology, University of Minnesota, Minneapolis.
Dermatitis. 2017 Sep/Oct;28(5):317-322. doi: 10.1097/DER.0000000000000275.
Wet wipes are a significant allergen source for anogenital allergic contact dermatitis.
The aim of the study was to calculate the frequency of potentially allergenic ingredients in personal hygiene wet wipes.
Ingredient lists from brand name and generic personal hygiene wet wipes from 4 large retailers were compiled.
In the 54 personal hygiene wet wipes evaluated, a total of 132 ingredients were identified (average of 11.9 ingredients per wipe). The most common ingredients were Aloe barbadensis (77.8%), citric acid (77.8%), fragrance (72.2%), sorbic acid derivatives (63.0%), tocopherol derivatives (63.0%), glycerin (59.3%), phenoxyethanol (55.6%), disodium cocoamphodiacetate (53.7%), disodium ethylenediaminetetraacetic acid (EDTA) (42.6%), propylene glycol (42.6%), iodopropynyl butylcarbamate (40.7%), chamomile extracts (38.9%), sodium benzoate (35.2%), bronopol (22.2%), sodium citrate (22.2%), lanolin derivatives (20.4%), parabens (20.4%), polyethylene glycol derivatives (18.5%), disodium phosphate (16.7%), dimethylol dimethyl hydantoin (DMDM) (14.8%), and cocamidopropyl propylene glycol (PG)-dimonium chloride phosphate (11.1%). Of note, methylisothiazolinone (5.6%) was uncommon; methylchloroisothiazolinone was not identified in the personal hygiene wet wipes examined.
There are many potential allergens in personal hygiene wet wipes, especially fragrance and preservatives.
湿纸巾是引起肛门生殖器过敏性接触性皮炎的一个重要过敏原来源。
本研究旨在计算个人卫生湿巾中潜在过敏原成分的频率。
编译了来自 4 家大型零售商的品牌和通用个人卫生湿巾的成分清单。
在评估的 54 个个人卫生湿巾中,共鉴定出 132 种成分(每种湿巾平均 11.9 种成分)。最常见的成分是库拉索芦荟(77.8%)、柠檬酸(77.8%)、香料(72.2%)、山梨酸衍生物(63.0%)、生育酚衍生物(63.0%)、甘油(59.3%)、苯氧乙醇(55.6%)、椰油两性二乙酸二钠(53.7%)、乙二胺四乙酸二钠(EDTA)(42.6%)、丙二醇(42.6%)、碘丙炔醇丁基氨甲酸酯(40.7%)、洋甘菊提取物(38.9%)、苯甲酸钠(35.2%)、溴硝醇(22.2%)、柠檬酸钠(22.2%)、羊毛脂衍生物(20.4%)、对羟基苯甲酸酯(20.4%)、聚乙二醇衍生物(18.5%)、磷酸二氢钠(16.7%)、二羟甲基二甲基乙内酰脲(DMDM)(14.8%)和椰油酰胺丙基 PG-二甲基氯化铵磷酸酯(11.1%)。值得注意的是,甲基异噻唑啉酮(5.6%)并不常见;在研究的个人卫生湿巾中未发现甲基氯异噻唑啉酮。
个人卫生湿巾中存在许多潜在过敏原,尤其是香料和防腐剂。