Holland E J, Bennett S R, Brannian R, Osborne J C, Goeken J A, Krachmer J H
Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City 52242.
Am J Ophthalmol. 1988 Apr 15;105(4):357-60. doi: 10.1016/0002-9394(88)90297-8.
To investigate the risk of cytomegalovirus transmission by corneal transplantation, we quantitated anticytomegalovirus IgG levels of donor, preoperative, and postoperative serum samples. Of 118 patients, 79 (67%) were seropositive preoperatively. Twenty-five patients who were seronegative preoperatively received a graft from a positive donor and two (8%) seroconverted. Eleven patients who were seronegative preoperatively received a graft from a negative donor and one (9%) seroconverted. None of the patients who seroconverted had a febrile illness and all three grafts were clear.
为了研究角膜移植传播巨细胞病毒的风险，我们对供体、术前和术后血清样本中的抗巨细胞病毒IgG水平进行了定量分析。在118例患者中，79例（67%）术前血清学呈阳性。25例术前血清学阴性的患者接受了来自阳性供体的移植物，其中2例（8%）发生了血清学转换。11例术前血清学阴性的患者接受了来自阴性供体的移植物，其中1例（9%）发生了血清学转换。发生血清学转换的患者均无发热性疾病，且所有3例移植物均清晰。
