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认知障碍、死亡率与大量非计划性急症入院老年患者出院特征之间的关系:一项回顾性观察研究。

The relationship between cognitive impairment, mortality and discharge characteristics in a large cohort of older adults with unscheduled admissions to an acute hospital: a retrospective observational study.

机构信息

University of Portsmouth - School of Health Sciences and Social Work, Portsmouth, UK.

Portsmouth Hospitals NHS Trust, Portsmouth, UK.

出版信息

Age Ageing. 2017 Sep 1;46(5):794-801. doi: 10.1093/ageing/afx022.

Abstract

BACKGROUND

older people with dementia admitted to hospital for acute illness have higher mortality and longer hospital stays compared to those without dementia. Cognitive impairment (CI) is common in older people, and they may also be at increased risk of poor outcomes.

METHODS

retrospective observational study of unscheduled admissions aged ≥75 years. Admission characteristics, mortality rates and discharge outcomes were compared between three groups: (i) known dementia diagnosis (DD), (ii) CI but no diagnosis of dementia and (iii) no CI.

RESULTS

of 19,269 admissions (13,652 patients), 19.8% had a DD, 11.6% had CI and 68.6% had neither. Admissions with CI or DD were older and had more females than those with no CI, and were more likely to be admitted through the Emergency Department (88.4% and 90.7%, versus 82.0%) and to medical wards (89.4% and 84.4%, versus 76.8%). Acuity levels at admission were similar between the groups. Patients with CI or DD had more admissions at 'high risk' from malnutrition than patients with no CI (28.0% and 33.7% versus 17.5%), and a higher risk of dying in hospital (11.8% [10.5-13.3] and 10.8% [9.8-11.9] versus (6.6% [6.2-7.0])).

CONCLUSIONS

the admission characteristics, mortality and length of stay of patients with CI resemble those of patients with diagnosed dementia. Whilst attention has been focussed on the need for additional support for people with dementia, patients with CI, which may include those with undiagnosed dementia or delirium, appear to have equally bad outcomes from hospitalisation.

摘要

背景

与无痴呆症的患者相比,因急性疾病住院的老年痴呆症患者的死亡率和住院时间更长。认知障碍(CI)在老年人中很常见,他们也可能面临不良预后的风险增加。

方法

对≥75 岁的非计划性入院患者进行回顾性观察性研究。比较三组患者的入院特征、死亡率和出院结局:(i)已知痴呆症诊断(DD),(ii)有 CI 但无痴呆症诊断,(iii)无 CI。

结果

19269 例入院患者(13652 例患者)中,19.8%有 DD,11.6%有 CI,68.6%无 CI。有 CI 或 DD 的入院患者比无 CI 的患者年龄更大,女性更多,更有可能通过急诊部入院(88.4%和 90.7%,82.0%),更有可能入住内科病房(89.4%和 84.4%,76.8%)。入院时的病情严重程度在各组之间相似。有 CI 或 DD 的患者比无 CI 的患者营养不良风险更高(28.0%和 33.7%,17.5%),住院死亡率更高(11.8%[10.5-13.3]和 10.8%[9.8-11.9],6.6%[6.2-7.0])。

结论

CI 患者的入院特征、死亡率和住院时间与确诊痴呆症患者相似。虽然人们一直关注需要为痴呆症患者提供额外支持,但 CI 患者(可能包括未确诊的痴呆症或谵妄患者)似乎同样面临住院不良预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68b5/5860577/79396336c278/afx022f01.jpg

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