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睾丸癌治疗中依赖医生的预后变量

Physician-dependent prognostic variables in the management of testicular cancer.

作者信息

Thornhill J A, Walsh A, Conroy R M, Fennelly J J, Kelly D G, Fitzpatrick J M

机构信息

Irish Testicular Tumour Registry, Dublin, Ireland.

出版信息

Br J Urol. 1988 Mar;61(3):244-9.

PMID:2833973
Abstract

A study of 246 cases of germ cell testicular cancer in Ireland between 1980 and 1985 confirmed that the personnel and the manner of management can significantly influence the outcome. Inadequate staging by omitting marker assays or CT scan reduced prognosis. Failure to use standard chemotherapy (PVB, BEP, POMBACE, VAB) or a reduced dosage diminished survival. Regular investigations are necessary during treatment, including marker assays, chest X-ray and CT scan. Frequent monitoring is important in later follow-up. Management by a urologist improved survival, especially if he was involved from the outset. The results also favoured the concept of combined management by a urologist and an oncologist.

摘要

一项针对1980年至1985年间爱尔兰246例睾丸生殖细胞癌病例的研究证实,医疗人员及管理方式会对治疗结果产生重大影响。因遗漏标志物检测或CT扫描而导致分期不充分会降低预后。未使用标准化化疗方案(PVB、BEP、POMBACE、VAB)或剂量减少会降低生存率。治疗期间进行定期检查很有必要,包括标志物检测、胸部X光和CT扫描。在后续随访中频繁监测也很重要。由泌尿科医生进行管理可提高生存率,尤其是如果他从一开始就参与治疗。研究结果也支持泌尿科医生和肿瘤学家联合管理的理念。

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