Carroll Steven L
Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.
J Neuropathol Exp Neurol. 2017 Apr 1;76(4):255-257. doi: 10.1093/jnen/nlx013.
Saltatory conduction is the process by which action potentials are rapidly and efficiently propagated along myelinated axons. In the peripheral nervous system, saltatory conduction is made possible by a series of morphologically and molecularly distinct subdomains in both axons and their associated myelinating Schwann cells. This review briefly summarizes current knowledge on the molecular structure and physiology of the node of Ranvier and adjacent regions of the axoglial unit in peripheral nerve.
跳跃传导是动作电位沿有髓轴突快速且高效传播的过程。在周围神经系统中,轴突及其相关的髓鞘形成施万细胞中一系列形态和分子上不同的亚结构域使得跳跃传导成为可能。本综述简要总结了关于周围神经中朗飞结及其轴突-神经胶质单元相邻区域的分子结构和生理学的当前知识。