Fan Q C, Wu P F, Dai G J, Zhang G X, Zhang T, Xue Q, Shi H Q, Wang J Y
College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.
College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China
Genet Mol Res. 2017 Mar 22;16(1):gmr-16-01-gmr.16019431. doi: 10.4238/gmr16019431.
Reproductive traits have long been studied and have an important influence on chicken breeding. To identify quantitative trait loci affecting reproductive traits, a genome-wide analysis of a Chinese chicken breed was performed to analyze age at first egg body weight at first egg, first egg weight, egg weight at the age of 300 days, egg weight at the age of 462 days, egg number at the age of 300 days, egg number between the ages of 300 and 462 days and egg number at the age of 462 days. Nineteen SNPs related to reproductive traits were presented (P < 1.80E-6). Nine of the 19 SNPs had a significant effect on BWF, six SNPs were significantly associated with egg weight, and four SNPs were significantly associated with egg number. These SNPs were located near to or in 17 genes including FAM184B, HTT, KCNH7, CDC42BPA, KCNIP4, GJA5, CBFB, and GPC6. The present results may be beneficial for reproductive research and may be used in marker-assisted selection in future studies. These results could potentially benefit further breeding programs, especially in Jinghai Yellow Chicken.
生殖性状长期以来一直受到研究，并且对鸡的育种有重要影响。为了鉴定影响生殖性状的数量性状基因座，对一个中国鸡品种进行了全基因组分析，以分析开产日龄、开产体重、首枚蛋重、300日龄蛋重、462日龄蛋重、300日龄产蛋数、300至462日龄产蛋数以及462日龄产蛋数。共呈现出19个与生殖性状相关的单核苷酸多态性（SNP）（P < 1.80E-6）。这19个SNP中的9个对开产体重有显著影响，6个SNP与蛋重显著相关，4个SNP与产蛋数显著相关。这些SNP位于包括FAM184B、HTT、KCNH7、CDC42BPA、KCNIP4、GJA5、CBFB和GPC6在内的17个基因附近或内部。目前的结果可能有益于生殖研究，并可在未来研究中用于标记辅助选择。这些结果可能会使进一步的育种计划受益，尤其是在京海黄鸡方面。
