Karayagiz A H, Erturk T, Cakir U, Berber I
Transplant Center, Acibadem International Hospital, Acıbadem University, Istanbul, Turkey.
Transplant Center, Acibadem International Hospital, Acıbadem University, Istanbul, Turkey.
Transplant Proc. 2017 Apr;49(3):411-414. doi: 10.1016/j.transproceed.2017.01.035.
The aim of this study was to compare the results of standard laparoscopic donor nephrectomy with vaginal extraction (SLDN-VE) and laparoendoscopic single-site donor nephrectomy with vaginal extraction (LESSDN-VE).
We analyzed the data of 95 female donors who underwent SLDN-VE (group I; n = 87) and LESSDN-VE (group II; n = 8) in our center. Parameters regarding donor age, body mass index (BMI), length of hospitalization, duration of surgical procedure, amount of blood loss, warm and cold ischemia times, side of graft nephrectomy, number of renal arteries and veins, postoperative visual analog pain scores at 6th and 12th hours (VAS6, VAS12), peri-and postoperative complications of donors and recipients, and graft function at discharge and follow-up were compared between the 2 groups.
No significant difference regarding donor age, mean operative time, amount of blood loss, or warm ischemia time was observed between the 2 groups. However, BMI (P = .018) and pain scores (VAS6: P = .047; VAS12: P = .009) were lower and length of hospitalization (P = .005) shorter in group II. On the other hand, cold ischemia time (P = .047) was lower in group I. No peri- or postoperative complications occurred for donors and recipients in both groups. Graft function at discharge and during follow-up were similar in both groups.
Because our first priority is to minimize the morbidity of donors, LESSDN-VE can be chosen in selected female donors for not only decreased pain and hospital stay, but also for better cosmetic outcomes.
本研究旨在比较标准腹腔镜供体肾切除术联合经阴道取出术（SLDN-VE）与单孔腹腔镜供体肾切除术联合经阴道取出术（LESSDN-VE）的结果。
我们分析了在本中心接受SLDN-VE（I组；n = 87）和LESSDN-VE（II组；n = 8）的95名女性供体的数据。比较了两组之间关于供体年龄、体重指数（BMI）、住院时间、手术时间、失血量、热缺血和冷缺血时间、移植肾切除侧、肾动静脉数量、术后第6小时和第12小时的视觉模拟疼痛评分（VAS6、VAS12）、供体和受体的围手术期及术后并发症，以及出院时和随访时的移植肾功能等参数。
两组之间在供体年龄、平均手术时间、失血量或热缺血时间方面未观察到显著差异。然而，II组的BMI（P = 0.018）和疼痛评分（VAS6：P = 0.047；VAS12：P = 0.009）较低且住院时间（P = 0.005）较短。另一方面，I组的冷缺血时间（P = 0.047）较低。两组的供体和受体均未发生围手术期或术后并发症。两组出院时和随访期间的移植肾功能相似。
由于我们的首要任务是将供体的发病率降至最低，因此对于选定的女性供体，可以选择LESSDN-VE，这不仅可以减轻疼痛和缩短住院时间，还能获得更好的美容效果。
