Soudet S, Becquart C, Dezoteux F, Faure K, Staumont-Salle D, Delaporte E
Service de médecine interne, hôpital Claude-Huriez, CHRU, 59037 Lille cedex, France.
Service de dermatologie, hôpital Claude-Huriez, CHRU, 59037 Lille cedex, France; Faculté de médecine, université de Lille 2, 59045 Lille cedex, France.
Ann Dermatol Venereol. 2017 Jan;144(1):45-48. doi: 10.1016/j.annder.2016.09.045. Epub 2016 Oct 26.
Bacillus cereus is a ubiquitous telluric organism. B. cereus endocarditis is a rare condition seen mostly in prosthetic heart valves and among intravenous drug users. We report a new case of a patient without risk factors and with a good clinical outcome not requiring valve replacement.
In October 2014, a 50-year-old woman was referred to the dermatology department of Lille University Hospital for lower-limb wounds developing 6 months earlier. She presented fever without clinical signs of infection, except for the lower-limbs wounds. Blood cultures revealed the presence of B. cereus. Transesophageal echocardiography was performed and revealed two foci of aortic valve vegetation with a diameter of 5mm. After bacterial sensitivity testing, rifampicin and levofloxacin treatment was given for six weeks, with complete remission. A skin graft was performed and good improvement was seen.
Nineteen cases of B. cereus endocarditis have been described previously, only one of which was without risk factors. We described a case of complete remission after a 6-week course of antibiotics. Our case demonstrates that BC should not be considered as a blood culture contamination, and that treatment may be complex due to antibiotic resistance.
蜡样芽孢杆菌是一种广泛存在的陆生生物。蜡样芽孢杆菌性心内膜炎是一种罕见疾病,多见于人工心脏瓣膜患者及静脉吸毒者。我们报告一例无危险因素且临床结局良好、无需进行瓣膜置换的新病例。
2014年10月,一名50岁女性因6个月前出现的下肢伤口被转诊至里尔大学医院皮肤科。除下肢伤口外,她有发热症状,但无感染的临床体征。血培养显示存在蜡样芽孢杆菌。经食管超声心动图检查发现主动脉瓣上有两个直径为5毫米的赘生物。细菌敏感性试验后,给予利福平和左氧氟沙星治疗6周,症状完全缓解。进行了皮肤移植,情况明显改善。
此前已报道过19例蜡样芽孢杆菌性心内膜炎病例,其中只有1例无危险因素。我们描述了一例在接受6周抗生素疗程后完全缓解的病例。我们的病例表明,不应将蜡样芽孢杆菌视为血培养污染,而且由于抗生素耐药性,治疗可能会很复杂。