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肠系膜上动脉动脉瘤的管理:单中心16例经验

The Management of Superior Mesenteric Artery Aneurysm: Experience with 16 Cases in a Single Center.

作者信息

Zilun Li, Henghui Yin, Yang Zhao, Mian Wang, Guangqi Chang, Shenming Wang

机构信息

Division of Vascular Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Division of Vascular Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

出版信息

Ann Vasc Surg. 2017 Jul;42:120-127. doi: 10.1016/j.avsg.2016.11.014. Epub 2017 Mar 22.

DOI:10.1016/j.avsg.2016.11.014
PMID:28341504
Abstract

BACKGROUND

Superior mesenteric artery aneurysm (SMAA) represents a rare but potentially fatal condition. This study aimed to present the individual management protocol of SMAA in our center and to discuss a potential preliminary treatment algorithm.

METHODS

SMAA patients treated in our center between January 2007 and December 2014 were retrospectively reviewed on January 2015.

RESULTS

Sixteen patients with SMAA were identified, including 1 female and 15 males, with a mean age of 48.9 ± 12.9 years. Three patients (3/16, 18.8%) were treated by multiple overlapping bare stents and one (1/16, 6.3%) initially by a single bare stent. Two cases (2/16, 12.5%) were treated by a covered stent implantation, but one of those suffered from SMAA rupture 7 days later, whereas the other had inner-stent thrombosis one month after discharge and died from multiple organ-dysfunction syndrome. Nine patients (9/16, 56.2%) received conservative therapy, one of who received multiple overlapping bare stents implantations for persistent abdominal pain. One patient underwent open surgery. There were 2 major complications, with no death during hospitalization and 1 death during follow-up.

CONCLUSIONS

SMAA treatment needs to be individually prescribed, based on clinical manifestation, anatomy, and etiology. Multiple overlapping bare stents are safe and effective in selective patients with SMAA, and covered stents should be used with caution to avoid covering proximal branches; open surgery should be reserved for patients with suspected intestinal necrosis.

摘要

背景

肠系膜上动脉动脉瘤(SMAA)是一种罕见但可能致命的疾病。本研究旨在介绍我们中心SMAA的个体化治疗方案,并讨论一种潜在的初步治疗算法。

方法

2015年1月对2007年1月至2014年12月在我们中心接受治疗的SMAA患者进行回顾性分析。

结果

共确定16例SMAA患者,其中女性1例,男性15例,平均年龄48.9±12.9岁。3例患者(3/16,18.8%)采用多个重叠裸支架治疗,1例患者(1/16,6.3%)最初采用单个裸支架治疗。2例患者(2/16,12.5%)接受覆膜支架植入治疗,但其中1例在7天后发生SMAA破裂,另1例在出院后1个月发生支架内血栓形成,死于多器官功能障碍综合征。9例患者(9/16,56.2%)接受保守治疗,其中1例因持续性腹痛接受多个重叠裸支架植入治疗。1例患者接受了开放手术。发生2例严重并发症,住院期间无死亡,随访期间死亡1例。

结论

SMAA的治疗需要根据临床表现、解剖结构和病因进行个体化制定。多个重叠裸支架对选择性SMAA患者安全有效,使用覆膜支架时应谨慎,避免覆盖近端分支;对于疑似肠坏死的患者应保留开放手术。

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