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血管内射频消融治疗血栓闭塞性脉管炎(伯格氏病)的疗效

Efficacy of Endovascular Radiofrequency Ablation for Thromboangiitis Obliterans (Buerger's Disease).

作者信息

Tang Jingdong, Gan Shujie, Zheng Miao, Jiang Yongxin, Feng Yiwen, Miao Jiong

机构信息

Department of Vascular Surgery, Shanghai Pudong Hospital, Fudan Affiliated Pudong Medical Center, Shanghai, China.

Department of Vascular Surgery, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, China.

出版信息

Ann Vasc Surg. 2017 Jul;42:78-83. doi: 10.1016/j.avsg.2016.11.012. Epub 2017 Mar 22.

Abstract

BACKGROUND

This study aimed to evaluate the efficacy of endovascular radiofrequency ablation (RFA) for the treatment of thromboangiitis obliterans (TAO).

METHODS

Total 30 males (median age: 46.00 years, interquartile range: 42.00-51.25 years) with unilateral TAO in the lower extremity underwent RFA were retrospectively enrolled from January 2013 and October 2013. The pre-operative and post-operative digital subtraction angiographic (DSA) images were recorded. Pain scores preoperatively and postoperatively were assessed according to the World Health Organization Pain Guideline. The values of ankle brachial index (ABI) at pre-operation, post-operation, 2 weeks and 2 years after surgery were all recorded and analyzed. Additionally, a 2-year follow up was performed by a computed tomographic angiography (CTA) image.

RESULTS

The DSA images indicated that occlusion of femoral artery was improved after surgery. Moreover, there was no recurrence of TAO at 2 years of follow-up based on the CTA images. The pain score (P < 0.001) was significantly deceased after surgery. The values of ABI at postoperation, 2 weeks after surgery, and 2 years after surgery were all significantly higher than the preoperative ABI (P < 0.001). Furthermore, the values of ABI at 2 weeks after surgery and 2 years after surgery were all significantly higher than the postoperative ABI (P < 0.001).

CONCLUSIONS

These results supported the application of endovascular RFA for treating TAO.

摘要

背景

本研究旨在评估血管内射频消融术(RFA)治疗血栓闭塞性脉管炎(TAO)的疗效。

方法

回顾性纳入2013年1月至2013年10月期间30例单侧下肢TAO男性患者(中位年龄:46.00岁,四分位间距:42.00 - 51.25岁),接受RFA治疗。记录术前和术后数字减影血管造影(DSA)图像。根据世界卫生组织疼痛指南评估术前和术后疼痛评分。记录并分析术前、术后、术后2周和术后2年的踝肱指数(ABI)值。此外,通过计算机断层血管造影(CTA)图像进行2年随访。

结果

DSA图像显示术后股动脉闭塞情况有所改善。此外,根据CTA图像,随访2年时TAO无复发。术后疼痛评分显著降低(P < 0.001)。术后、术后2周和术后2年的ABI值均显著高于术前ABI(P < 0.001)。此外,术后2周和术后2年的ABI值均显著高于术后ABI(P < 0.001)。

结论

这些结果支持血管内RFA用于治疗TAO。

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