辅助干扰素-γ免疫疗法治疗进展性脑诺卡菌脓肿患者。
Adjuvant interferon-gamma immunotherapy in a patient with progressive cerebral Nocardia abscesses.
机构信息
Department of Internal Medicine, Radboud university medical center, Radboud Institute for Molecular Life Sciences (RILMS), Nijmegen, the Netherlands; Department of Intensive Care Medicine, Radboud university medical center, Radboud Institute for Molecular Life Sciences (RILMS), Nijmegen, the Netherlands.
Department of Internal Medicine, Radboud university medical center, Radboud Institute for Molecular Life Sciences (RILMS), Nijmegen, the Netherlands.
出版信息
Int J Infect Dis. 2017 Jun;59:25-28. doi: 10.1016/j.ijid.2017.03.013. Epub 2017 Mar 22.
Despite advances in medical care, mortality due to cerebral Nocardia abscesses remains unacceptably high. The case of a typical immunocompromised patient, who deteriorated clinically despite optimal antimicrobial treatment, is reported here. Adjuvant immunotherapy with interferon-gamma resulted in partial restoration of the immune response and a corresponding clinical and radiographic recovery.
尽管医疗技术取得了进步，但因脑部诺卡氏菌脓肿导致的死亡率仍然高得令人无法接受。本文报告了一例典型免疫功能低下患者的病例，尽管采用了最佳的抗菌治疗，但病情仍在恶化。用干扰素-γ进行辅助免疫治疗导致免疫反应部分恢复，相应的临床和影像学也得到了恢复。
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