Wacher Niels H, Reyes-Sánchez Mario, Vargas-Sánchez Héctor Raúl, Gamiochipi-Cano Mireya, Rascón-Pacheco Ramón Alberto, Gómez-Díaz Rita A, Doubova Svetlana V, Valladares-Salgado Adán, Sánchez-Becerra Martha Catalina, Méndez-Padrón Araceli, Valdez-González Leticia A, Mondragón-González Rafael, Cruz Miguel, Salinas-Martinez Ana María, Garza-Sagástegui María Guadalupe, Hernández-Rubí Jaime, González-Hermosillo Arturo, Borja-Aburto Víctor H
Unidad de Investigación en Epidemiología Clínica, UMAE Hospital de Especialidades, Centro Médico Siglo XXI, IMSS, Mexico City, Mexico.
División de Medicina Familiar, Unidad de Atención Primaria, IMSS, Mexico City, Mexico.
Prim Care Diabetes. 2017 Jun;11(3):297-304. doi: 10.1016/j.pcd.2017.02.005. Epub 2017 Mar 23.
Describe stepwise strategies (electronic chart review, patient preselection, call-center, personnel dedicated to recruitment) for the successful recruitment of >5000 type 2 diabetes patients in four months.
Twenty-five family medicine clinics from Mexico City and the State of Mexico participated: 13 usual care, 6 specialized diabetes care and 6 chronic disease care. Appointments were scheduled from 11/3/2015 to 3/31/2016. Phone calls were generated automatically from an electronic database. A telephone questionnaire verified inclusion criteria, and scheduled an appointment, with a daily report of appointments, patient attendance, acceptance rate, and questionnaire completeness. Another recruitment log reviewed samples collected. Absolute number (percentage) of patients are reported. Means and standard deviations were estimated for continuous variables, χ test and independent "t" tests were used. OR and 95% CI were estimated.
14,358 appointments were scheduled, 9146 (63.7%) attended their appointment: 5710 (62.4%) fulfilled inclusion criteria and 5244 agreed to participate (91.8% acceptance). Those accepting participation were more likely women, younger and with longer disease duration (p<0.05). The cost of the call-center service was $3,010,000.00 Mexican pesos (∼$31.70 USD per recruited patient).
Stepwise strategies recruit a high number of patients in a short time. Call centers offer a low cost per patient.
描述逐步推进的策略（电子病历审查、患者预选、呼叫中心、专门负责招募的人员），以便在四个月内成功招募5000多名2型糖尿病患者。
来自墨西哥城和墨西哥州的25家家庭医学诊所参与其中：13家提供常规护理，6家提供专门的糖尿病护理，6家提供慢性病护理。预约时间为2015年11月3日至2016年3月31日。电话由电子数据库自动生成。通过电话问卷核实纳入标准，并安排预约，同时每日报告预约情况、患者就诊情况、接受率和问卷完整性。另一份招募记录审查所收集的样本。报告患者的绝对数（百分比）。对连续变量估计均值和标准差，使用χ检验和独立t检验。估计比值比（OR）和95%置信区间（CI）。
共安排了14358次预约，9146人（63.7%）前来就诊：5710人（62.4%）符合纳入标准，5244人同意参与（接受率为91.8%）。接受参与的患者更可能是女性、更年轻且病程更长（p<0.05）。呼叫中心服务的成本为3010000.00墨西哥比索（约合每位招募患者31.70美元）。
逐步推进的策略能在短时间内招募大量患者。呼叫中心每位患者的成本较低。
