人羊膜同种异体移植在鼻尖再上皮化中的应用
Utility of human amniotic membrane allograft in re-epithelialization of the nasal tip.
作者信息
Dennis D'Antonio C, Turnock Adam R, Sutton Collin, Chastant Bradley, Vanderlan Wesley B
机构信息
Department of Otolaryngology , Louisiana State University Health Sciences Center New Orleans , LA 70112 , USA.
Department of Medical Education , Tulane University School of Medicine New Orleans , LA 70112 , USA.
出版信息
J Surg Case Rep. 2016 Oct 22;2016(10):rjw174. doi: 10.1093/jscr/rjw174. eCollection 2016 Oct.
Variations in skin thickness and contours pose significant challenges to reconstruction of the lower third of the nose. Human amniotic membrane allograft offers a potential alternative to tissue transfer in reconstruction of the lower third of the nose. We reviewed the procedure and photographs of a healthy 56-year-old male with a 22 × 18 mm lower third nasal defect involving full thickness skin and subcutaneous tissue. Following preparation for grafting, dehydrated human amniotic membrane was fashioned to the dimensions of the defect and applied. No further surgical intervention was provided for 3 months. Complete re-epithelialization of the nasal and adjacent defects was achieved with minimal scar formation. Human amniotic membrane allograft provides an efficacious and cosmetically acceptable alternative to local and regional tissue transfer.
皮肤厚度和轮廓的变化给鼻下三分之一的重建带来了重大挑战。人羊膜同种异体移植为鼻下三分之一的重建提供了一种潜在的组织转移替代方案。我们回顾了一名56岁健康男性的手术过程及照片，该患者鼻下三分之一处有一个22×18毫米的全层皮肤和皮下组织缺损。在准备移植后，将脱水人羊膜制作成缺损尺寸并应用。3个月内未进行进一步手术干预。鼻及相邻缺损实现了完全上皮化，瘢痕形成 minimal。人羊膜同种异体移植为局部和区域组织转移提供了一种有效且美容效果可接受的替代方案。
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